Gene Information gene info

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GENE：IL27RA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol IL27RA
FullNmae interleukin 27 receptor subunit alpha
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17290
EnsembleID ENSG00000104998
Uniprot Q6UWB1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
IL27RA pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
IL27RA ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
IL27RA GO:0002827,GO:0002829,GO:0004888,GO:0005515,GO:0005886,GO:0006955,GO:0007166,GO:0009897,GO:0019221,GO:0019955,GO:0032700,GO:0032715,GO:0032720,GO:0032729,GO:0043235,GO:0043524,GO:0045509,GO:0048302,GO:0050830,GO:0070106,GO:2000317,GO:2000408

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
IL27RA hsa:9466 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
IL27RA hsa:9466 path:hsa04630 JAK-STAT signaling pathway - Homo sapiens (human)
IL27RA hsa:9466 path:hsa04659 Th17 cell differentiation - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
IL27 IL27RA 12121660 17318299 18988627 23331499 stimulation N/A SignaLink,SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 IL27RA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 IL27RA 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF IL27RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A IL27RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF IL27RA 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
IL27RA JAK1 25361965 interaction type N/A PTMCode2
JAK1 IL27RA 25361965 interaction type N/A PTMCode2
EBI3 IL27RA 25361965 interaction type N/A PTMCode2
IL27RA EBI3 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
STAT1 IL27RA 12734330 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CLDN2 IL27RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
SLC41A2 IL27RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AP1G2 IL27RA 25348397 N/A physical interaction ComPPI
MAPK8 IL27RA 12734330 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
CANX IL27RA 25348397 N/A physical interaction ComPPI
JAK1 IL27RA 25348397 N/A physical interaction ComPPI
SRPRA IL27RA 25348397 N/A physical interaction ComPPI
FGFR1 IL27RA 25348397 N/A physical interaction ComPPI
GLMN IL27RA 25348397 N/A physical interaction ComPPI
MT-CO1 IL27RA 25348397 N/A physical interaction ComPPI
IL27RA EBI3 12121660 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IL27RA IL27 12121660 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
IL27RA POTEE 25348397 N/A physical interaction ComPPI
IL27RA TMX4 25348397 N/A physical interaction ComPPI
IL27RA DNAJC18 25348397 N/A physical interaction ComPPI
IL27RA FNDC3A 25348397 N/A physical interaction ComPPI
IL27RA TMEM30B 25348397 N/A physical interaction ComPPI
IL27RA DEPDC1 25348397 N/A physical interaction ComPPI
IL27RA ULBP3 25348397 N/A physical interaction ComPPI
IL27RA B4GALT5 25348397 N/A physical interaction ComPPI
IL27RA RHBDD3 25348397 N/A physical interaction ComPPI
IL27RA PLD6 25348397 N/A physical interaction ComPPI
IL27RA LENG8 25348397 N/A physical interaction ComPPI
IL27RA TMX1 25348397 N/A physical interaction ComPPI
IL27RA TNFSF9 25348397 N/A physical interaction ComPPI
IL27RA B4GALT1 25348397 N/A physical interaction ComPPI
IL27RA GNB2 25348397 N/A physical interaction ComPPI
IL27RA NDC1 25348397 N/A physical interaction ComPPI
IL27RA CELSR2 25348397 N/A physical interaction ComPPI
IL27RA PLXNB2 25348397 N/A physical interaction ComPPI
IL27RA NRP1 25348397 N/A physical interaction ComPPI
IL27RA LRP11 25348397 N/A physical interaction ComPPI
IL27RA YIPF6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL27RA DERL3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
DEFB121 IL27RA 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IL27 IL27RA 12121660 14764690 27898060 stimulant N/A OmniPath

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