Gene Information gene info

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GENE：FEM1B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol FEM1B
FullNmae fem-1 homolog B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3649
EnsembleID ENSG00000169018
Uniprot Q9UK73

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
FEM1B pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEM1B parthanatos 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEM1B immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEM1B ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEM1B autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEM1B apoptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
FEM1B apoptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
FEM1B GO:0005123,GO:0005123,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0005737,GO:0005829,GO:0005829,GO:0006915,GO:0016567,GO:0031462,GO:0043161,GO:0051438,GO:0060442,GO:0060743,GO:0140627,GO:1902041,GO:1990756,GO:2000001

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FEM1B CUL2 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBX1 FEM1B 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
FEM1B ELOC 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
ELOB FEM1B 15601820 23180781 physical association anti tag coimmunoprecipitation InnateDB
NEDD8 FEM1B 21145461 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
AR FEM1B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 FEM1B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 FEM1B 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 FEM1B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 FEM1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002152A8 FEM1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 FEM1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 FEM1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005CF5F FEM1B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000072E4C FEM1B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F FEM1B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B FEM1B 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000007FBA FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000277201 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000052EA98 FEM1B 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 FEM1B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000054D341 FEM1B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000076995 FEM1B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000272A3D FEM1B 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A FEM1B 20371350 21572407 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C7662 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000184017 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075994C FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000009C45F FEM1B 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000555DA6 FEM1B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000003ABC4 FEM1B 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A4ABF FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000029D9F1 FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005D986D FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F0130 FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 FEM1B 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 FEM1B 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F FEM1B 22473208 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBX1 FEM1B 25361965 interaction type N/A PTMCode2
FEM1B RBX1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 FEM1B 25348397 N/A physical interaction ComPPI
TOMM22 FEM1B 25348397 N/A physical interaction ComPPI
TGFB1 FEM1B 25348397 N/A physical interaction ComPPI
DCUN1D1 FEM1B 25348397 N/A physical interaction ComPPI
CNTF FEM1B 25348397 N/A physical interaction ComPPI
RACK1 FEM1B 25348397 N/A physical interaction ComPPI
COPS5 FEM1B 25348397 N/A physical interaction ComPPI
GLI1 FEM1B 24076122 25348397 27898060 N/A physical interaction ComPPI,OmniPath
RBX1 FEM1B 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RAD9A FEM1B 25348397 N/A physical interaction ComPPI
MAPK8IP1 FEM1B 25348397 N/A physical interaction ComPPI
COPS2 FEM1B 25348397 N/A physical interaction ComPPI
EPN3 FEM1B 25348397 N/A physical interaction ComPPI
NEDD8 FEM1B 25348397 N/A physical interaction ComPPI
CUL2 FEM1B 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CHEK1 FEM1B 25348397 N/A physical interaction ComPPI
HTT FEM1B 23275563 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
GLMN FEM1B 25348397 N/A physical interaction ComPPI
COPS3 FEM1B 25348397 N/A physical interaction ComPPI
COPS4 FEM1B 25348397 N/A physical interaction ComPPI
COPS6 FEM1B 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
COPS8 FEM1B 25348397 N/A physical interaction ComPPI
SHKBP1 FEM1B 25348397 N/A physical interaction ComPPI
ELOB FEM1B 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELOC FEM1B 15601820 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HIF1AN FEM1B 17003112 24234451 25348397 hydroxylation reaction,physical association anti tag coimmunoprecipitation,two hybrid,hydroxylation reaction,physical interaction,hydroxylase assay ComPPI,IntAct
APAF1 FEM1B 10764728 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
TRIM25 FEM1B 25348397 N/A physical interaction ComPPI
WNT3A FEM1B 25348397 N/A physical interaction ComPPI
NKX3-1 FEM1B 25348397 N/A physical interaction ComPPI
GORASP1 FEM1B 25348397 N/A physical interaction ComPPI
GAK FEM1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
BSPRY FEM1B 25348397 N/A physical interaction ComPPI
KIF2B FEM1B 25348397 N/A physical interaction ComPPI
COPS7B FEM1B 25348397 N/A physical interaction ComPPI
FEM1B KIAA0319 12421765 14525934 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
FEM1B FAS 10542291 14525934 25348397 27898060 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD,OmniPath
FEM1B PPM1F 11559703 24234451 25348397 physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
FEM1B MVB12B 25348397 N/A physical interaction ComPPI
FEM1B DMWD 25348397 N/A physical interaction ComPPI
FEM1B CAMKMT 25348397 N/A physical interaction ComPPI
FEM1B ALDH1B1 25348397 N/A physical interaction ComPPI
FEM1B SLBP 25348397 N/A physical interaction ComPPI
FEM1B BPNT1 25348397 N/A physical interaction ComPPI
FEM1B FOXRED2 25348397 N/A physical interaction ComPPI
FEM1B OLFM2 25348397 N/A physical interaction ComPPI
FEM1B DLC1 25348397 N/A physical interaction ComPPI
FEM1B RAB41 25348397 N/A physical interaction ComPPI
FEM1B USP25 25348397 N/A physical interaction ComPPI
TRIM44 FEM1B 25348397 N/A physical interaction ComPPI
SYCE3 FEM1B 25348397 N/A physical interaction ComPPI
FEM1B FEM1B 10542291 14525934 N/A experimental interaction detection HPRD
ANKRD37 FEM1B 21723927 27898060 N/A N/A OmniPath

Visualization










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