Gene Information gene info

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GENE：ASF1A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ASF1A
FullNmae anti-silencing function 1A histone chaperone
LocusType gene with protein product
Status Approved
HGNC_id HGNC:20995
EnsembleID ENSG00000111875
Uniprot Q9Y294

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ASF1A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ASF1A GO:0000785,GO:0001649,GO:0003682,GO:0005515,GO:0005634,GO:0005634,GO:0005634,GO:0005654,GO:0005654,GO:0006281,GO:0006334,GO:0006335,GO:0031297,GO:0032991,GO:0035861,GO:0042393,GO:0042393,GO:0042692,GO:0140713,GO:0140861

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ASF1A 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ASF1A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ASF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ASF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ASF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ASF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR ASF1A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000007FBA ASF1A 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00002C0FCB ASF1A 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000DDD35 ASF1A 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00001AFC71 ASF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000028BB8 ASF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB ASF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C ASF1A 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TLK2 ASF1A 22135298 phosphorylation N/A PhosphoSite
ASF1A H3-3A 25361965 interaction type N/A PTMCode2
H3-3A ASF1A 25361965 interaction type N/A PTMCode2
ASF1A KAT2B 25361965 interaction type N/A PTMCode2
KAT2B ASF1A 25361965 interaction type N/A PTMCode2
ASF1A CHAF1A 25361965 interaction type N/A PTMCode2
CHAF1A ASF1A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HAT1 ASF1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PPP1CB ASF1A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MCM6 ASF1A 25348397 N/A physical interaction ComPPI
MCM2 ASF1A 24234451 25348397 26167883 association,physical association anti tag coimmunoprecipitation,two hybrid,light scattering,molecular sieving,pull down,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
H4C1 ASF1A 10759893 14525934 15664198 19862764 23075851 24234451 25348397 25416956 26167883 association,physical association two hybrid,experimental interaction detection,light scattering,molecular sieving,pull down,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ASF1A TAF1 12093919 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
ASF1A CHAF1B 11897662 14525934 16980972 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
ASF1A CHEK2 11172707 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
ASF1A TLK2 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
ASF1A TLK1 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo ComPPI,IntAct
ASF1A ASF1B 12842904 14525934 24234451 25348397 26496610 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD,IntAct
ASF1A HIRA 14525934 14652010 15621527 16537536 16980972 17242207 18378699 19029251 21414300 24234451 25348397 26496610 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,experimental interaction detection,isothermal titration calorimetry,pull down,x-ray crystallography,physical interaction,competition binding,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
ASF1A ST13 14525934 15664198 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
ASF1A PAFAH1B2 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ASF1A VPS28 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ASF1A H3-4 14525934 14718166 15664198 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
ASF1A TP53 25348397 N/A physical interaction ComPPI
ASF1A TP73 25348397 N/A physical interaction ComPPI
ASF1A HTATIP2 25348397 N/A physical interaction ComPPI
ASF1A CDAN1 22407294 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A IPO4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A NASP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A RBBP7 24234451 25348397 26496610 27705803 association anti tag coimmunoprecipitation,physical interaction,tandem affinity purification ComPPI,IntAct
ASF1A RBBP4 24234451 25348397 27705803 association physical interaction,tandem affinity purification ComPPI,IntAct
ASF1A MCM4 25348397 N/A physical interaction ComPPI
ASF1A MCM7 25348397 N/A physical interaction ComPPI
ASF1A TONSL 21113133 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ASF1A UBN1 19029251 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A MMS22L 25348397 N/A physical interaction ComPPI
ASF1A SARS1 25348397 N/A physical interaction ComPPI
ASF1A BTRC 25348397 N/A physical interaction ComPPI
ASF1A CUL1 25348397 N/A physical interaction ComPPI
ASF1A PML 25348397 N/A physical interaction ComPPI
ASF1A PRR3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ASF1A ZDHHC17 24234451 24705354 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ASF1A CENPB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A COPB1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A PPP1CA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A SPTBN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A ANKLE2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A CABIN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A RIF1 25348397 N/A physical interaction ComPPI
ASF1A ARFGAP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A CDIN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A UBN2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ASF1A PAN3 25348397 N/A physical interaction ComPPI
ASF1A PAN2 25348397 N/A physical interaction ComPPI
ASF1A PPTC7 25348397 N/A physical interaction ComPPI
ASF1A H3C15 24234451 25348397 26167883 association,physical association light scattering,molecular sieving,pull down,physical interaction ComPPI,IntAct
ASF1A ESR1 21217774 24234451 25348397 physical association two hybrid,phage display ComPPI,IntAct
ASF1A PTBP3 22575643 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CHAF1A ASF1A 11897662 14525934 19498464 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vivo ComPPI,HPRD,IntAct
H3C1 ASF1A 10759893 14525934 15664198 19410544 19498464 24234451 25348397 26167883 29568061 association,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,pull down,physical interaction,two hybrid array,in vitro,tandem affinity purification,two hybrid prey pooling approach,proximity-dependent biotin identification,two hybrid ComPPI,HPRD,IntAct
H3-3A ASF1A 14525934 15664198 23075851 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vivo ComPPI,HPRD,IntAct
CHEK2 ASF1A 11172707 11985607 27898060 inhibition N/A OmniPath
ASF1A H4C1 10759893 11985607 15664198 19862764 20393127 22407294 23075851 25416956 27898060 stimulant N/A OmniPath
ASF1A CHAF1B 11897662 16980972 27898060 stimulant N/A OmniPath
ASF1A H3C1 10759893 11985607 14718166 15664198 19410544 20393127 20504901 22407294 25281560 27898060 stimulant N/A OmniPath
ASF1A EP300 19270680 27898060 stimulant N/A OmniPath
TLK2 ASF1A 11470414 20016786 26496610 27898060 N/A N/A OmniPath

Visualization










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