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GENE：EIF3M

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF3M
FullNmae eukaryotic translation initiation factor 3 subunit M
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24460
EnsembleID ENSG00000149100
Uniprot Q7L2H7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF3M ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF3M GO:0001732,GO:0002183,GO:0003743,GO:0003743,GO:0005515,GO:0005829,GO:0005852,GO:0005852,GO:0005852,GO:0006413,GO:0016282,GO:0031369,GO:0033290,GO:0071541

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SRPK1 EIF3M 23180781 23602568 phosphorylation reaction protein kinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 EIF3M 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 EIF3M 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EIF3M 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EIF3M 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF3M 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EIF3M 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EIF3M 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZIC1 EIF3M 20713527 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000EC1BE EIF3M 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 EIF3M 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 EIF3M 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D EIF3M 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000039E1E1 EIF3M 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004C689A EIF3M 23708386 25416803 mrna cleavage,inhibition clip TarBase
URS00003808EC EIF3M 23708386 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EIF3G EIF3M 25348397 N/A physical interaction ComPPI
EIF1B EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3H EIF3M 18599441 19615732 23623729 24234451 25348397 association,physical association anti tag coimmunoprecipitation,mass spectrometry studies of complexes,pull down,physical interaction ComPPI,IntAct
RPN1 EIF3M 25348397 N/A physical interaction ComPPI
CIAO2B EIF3M 25348397 N/A physical interaction ComPPI
NPM1 EIF3M 25348397 N/A physical interaction ComPPI
TRAF6 EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
ACTB EIF3M 15047060 24234451 25348397 physical association molecular sieving ComPPI,IntAct
KEAP1 EIF3M 25348397 N/A physical interaction ComPPI
HSP90AB1 EIF3M 16263121 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3E EIF3M 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
NF2 EIF3M 25348397 N/A physical interaction ComPPI
JUN EIF3M 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
DLD EIF3M 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
UBE2N EIF3M 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
NTRK1 EIF3M 25348397 N/A physical interaction ComPPI
CD247 EIF3M 24234451 24502978 25348397 association pull down ComPPI,IntAct
HNRNPL EIF3M 25348397 N/A physical interaction ComPPI
CFTR EIF3M 25348397 N/A physical interaction ComPPI
EIF3C EIF3M 18599441 23623729 24234451 25348397 association,physical association mass spectrometry studies of complexes,pull down,physical interaction ComPPI,IntAct
EIF3F EIF3M 14525934 16169070 18599441 19748344 23623729 24234451 25348397 25416956 association,physical association anti tag coimmunoprecipitation,two hybrid,mass spectrometry studies of complexes,pull down,physical interaction,mammalian protein protein interaction trap,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,bimolecular fluorescence complementation,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
TNIK EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
HUWE1 EIF3M 25348397 N/A physical interaction ComPPI
EXOSC10 EIF3M 14525934 15231747 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
SRPK1 EIF3M 23602568 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
ABI3 EIF3M 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EGFR EIF3M 25348397 N/A physical interaction ComPPI
MMS19 EIF3M 25348397 N/A physical interaction ComPPI
EIF3I EIF3M 25348397 N/A physical interaction ComPPI
HSPB1 EIF3M 24234451 25277244 25348397 physical association reverse ras recruitment system,physical interaction ComPPI,IntAct
COPS4 EIF3M 25348397 N/A physical interaction ComPPI
TRIM25 EIF3M 25348397 N/A physical interaction ComPPI
EIF3J EIF3M 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EIF4A2 EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
BRCA1 EIF3M 25348397 N/A physical interaction ComPPI
PTP4A1 EIF3M 25348397 N/A physical interaction ComPPI
EIF3D EIF3M 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EIF3A EIF3M 17353931 18599441 23623729 24234451 25348397 association,physical association anti bait coimmunoprecipitation,transmission electron microscopy,mass spectrometry studies of complexes,molecular sieving,pull down,physical interaction,ion exchange chromatography,electron tomography ComPPI,IntAct
EIF3B EIF3M 18599441 24234451 25348397 physical association anti tag coimmunoprecipitation,mass spectrometry studies of complexes,physical interaction ComPPI,IntAct
EIF3L EIF3M 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
TADA2A EIF3M 25348397 N/A physical interaction ComPPI
EIF4A1 EIF3M 25348397 N/A physical interaction ComPPI
PRKAB1 EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
IKBKE EIF3M 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3K EIF3M 23623729 24234451 25348397 association pull down,physical interaction ComPPI,IntAct
EIF3M APP 25348397 N/A physical interaction ComPPI
EIF3M EIF3CL 25348397 N/A physical interaction ComPPI
EIF3M USP34 25348397 N/A physical interaction ComPPI
EIF3M AHCYL1 25348397 N/A physical interaction ComPPI
EIF3M MED4 25348397 N/A physical interaction ComPPI
EIF3M HERC2 24234451 25348397 29426014 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF3M HERC2P3 25348397 N/A physical interaction ComPPI
EIF3M PSMD12 25348397 N/A physical interaction ComPPI
EIF3M GPBP1L1 25348397 N/A physical interaction ComPPI
EIF3M CYLD 25348397 N/A physical interaction ComPPI
EIF3M G3BP1 25348397 N/A physical interaction ComPPI
EIF3M ACTR6 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3M GH1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3M NME2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3M TRIML2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF3M ZNF783 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF3M ZMYND10 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EIF3M PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF3M PDK1 25348397 N/A physical interaction ComPPI
EIF3M N 24234451 25294943 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
L1TD1 EIF3M 24234451 25702638 association anti bait coimmunoprecipitation IntAct
TPT1 EIF3M 24234451 27607350 association anti bait coimmunoprecipitation IntAct

Visualization










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