Gene Information gene info

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GENE：RPL28

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPL28
FullNmae ribosomal protein L28
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10330
EnsembleID ENSG00000108107
Uniprot P46779

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPL28 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPL28 autophagy 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RPL28 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
RPL28 GO:0002181,GO:0002181,GO:0003723,GO:0003735,GO:0003735,GO:0005515,GO:0005737,GO:0005829,GO:0006412,GO:0016020,GO:0022625,GO:0022625,GO:0022625,GO:0022625,GO:0022626,GO:0030425,GO:0036464,GO:0044297,GO:0045202,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPL28 hsa:6158 path:hsa03010 Ribosome - Homo sapiens (human)
RPL28 hsa:6158 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
RPL28 STAU1 16049941 23180781 physical association tandem affinity purification InnateDB
RNF2 RPL28 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RPL28 UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RPL28 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA RPL28 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RPL28 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RPL28 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 RPL28 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001012BC RPL28 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000035CC3E RPL28 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE RPL28 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000285DCB RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000CF1D2 RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004F859B RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000054DF42 RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00002FAA8C RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00000C48FA RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000044FD7 RPL28 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00004D84DB RPL28 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 RPL28 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A RPL28 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA RPL28 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 RPL28 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C RPL28 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002373FD RPL28 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000033B548 RPL28 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000419B5A RPL28 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004929F1 RPL28 25416803 26701625 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PPP1CC RPL28 24234451 25348397 28330616 association pull down ComPPI,IntAct
UBL4A RPL28 25348397 N/A physical interaction ComPPI
GABARAPL2 RPL28 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPS15 RPL28 25348397 N/A physical interaction ComPPI
UBE2D1 RPL28 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
SMAD4 RPL28 14525934 15231748 24234451 25348397 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
KEAP1 RPL28 25348397 N/A physical interaction ComPPI
MCM2 RPL28 25348397 N/A physical interaction ComPPI
GLYR1 RPL28 25348397 N/A physical interaction ComPPI
INO80B RPL28 25348397 N/A physical interaction ComPPI
GPRASP2 RPL28 25348397 N/A physical interaction ComPPI
JUN RPL28 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
COPS5 RPL28 25348397 N/A physical interaction ComPPI
RPL18A RPL28 25348397 N/A physical interaction ComPPI
GTF2I RPL28 25348397 N/A physical interaction ComPPI
CCNDBP1 RPL28 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
UBC RPL28 25348397 N/A physical interaction ComPPI
RPS3A RPL28 25348397 N/A physical interaction ComPPI
POLE RPL28 25348397 N/A physical interaction ComPPI
HNRNPU RPL28 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AKAP11 RPL28 25348397 N/A physical interaction ComPPI
RPL28 TMEM230 14525934 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RPL28 DCC 20434207 24234451 25348397 association anti bait coimmunoprecipitation,cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPL28 ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL28 TDRD3 25348397 N/A physical interaction ComPPI
RPL28 CUL2 25348397 N/A physical interaction ComPPI
RPL28 CDK2 25348397 N/A physical interaction ComPPI
RPL28 CUL1 25348397 N/A physical interaction ComPPI
RPL28 CAND1 25348397 N/A physical interaction ComPPI
RPL28 ESR1 21182205 24234451 25348397 association cosedimentation through density gradient,physical interaction ComPPI,IntAct
RPL28 MAGOH 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL28 PA2G4 15064750 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL28 FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
RPL28 ITGA4 25348397 N/A physical interaction ComPPI
RPL28 PAN2 25348397 N/A physical interaction ComPPI
RPL28 MAP2K5 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPL28 FBXO6 25348397 N/A physical interaction ComPPI
RPL28 TARDBP 25348397 N/A physical interaction ComPPI
RPL28 RPL8 25348397 N/A physical interaction ComPPI
RPL28 RPS10 25348397 N/A physical interaction ComPPI
RPL28 RPS18 25348397 N/A physical interaction ComPPI
RPL28 RPS19 25348397 N/A physical interaction ComPPI
RPL28 RPS23 25348397 N/A physical interaction ComPPI
RPL28 RPS29 25348397 N/A physical interaction ComPPI
RPL28 RPS2 25348397 N/A physical interaction ComPPI
RPL28 RPS3 25348397 N/A physical interaction ComPPI
RPL28 GRSF1 25348397 N/A physical interaction ComPPI
RPL28 TP53 25348397 N/A physical interaction ComPPI
RPL28 PCSK9 25348397 N/A physical interaction ComPPI
RPL28 BRCA1 25348397 N/A physical interaction ComPPI
RPL28 CCDC8 25348397 N/A physical interaction ComPPI
RPL28 RNF2 25348397 N/A physical interaction ComPPI
RPL28 RPL23A 25348397 N/A physical interaction ComPPI
RPL28 RPL13 25348397 N/A physical interaction ComPPI
RPL28 RPL19 25348397 N/A physical interaction ComPPI
RPL28 RPL21 25348397 N/A physical interaction ComPPI
RPL28 RPL3 25348397 N/A physical interaction ComPPI
RPL28 RPL34 25348397 N/A physical interaction ComPPI
RPL28 RPL36 25348397 N/A physical interaction ComPPI
RPL28 RPL5 25348397 N/A physical interaction ComPPI
RPL28 RPL7 25348397 N/A physical interaction ComPPI
RPL28 RPLP0 25348397 N/A physical interaction ComPPI
RPL28 RPLP0P6 25348397 N/A physical interaction ComPPI
RPL28 RPS11 25348397 N/A physical interaction ComPPI
RPL28 RPS15A 25348397 N/A physical interaction ComPPI
RPL28 RPS16 25348397 N/A physical interaction ComPPI
RPL28 RPL35 25348397 N/A physical interaction ComPPI
RPL28 RPL38 25348397 N/A physical interaction ComPPI
RPL28 RPLP1 25348397 N/A physical interaction ComPPI
RPL28 RPLP2 25348397 N/A physical interaction ComPPI
RPL28 RPS6 24234451 25348397 29568061 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
RPL28 XPO1 25348397 N/A physical interaction ComPPI
RPL28 KIF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL28 RC3H1 25348397 N/A physical interaction ComPPI
RPL28 NEPRO 25348397 N/A physical interaction ComPPI
RPL28 ZNF746 25348397 N/A physical interaction ComPPI
RPL28 H1-3 25348397 N/A physical interaction ComPPI
RPL28 H1-1 25348397 N/A physical interaction ComPPI
RPL28 H1-2 25348397 N/A physical interaction ComPPI
RPL28 PTPRK 25348397 N/A physical interaction ComPPI
RPL28 KLHL21 25348397 N/A physical interaction ComPPI
RPL28 FAT4 25348397 N/A physical interaction ComPPI
RPL28 ZDBF2 25348397 N/A physical interaction ComPPI
RPL28 HASPIN 25348397 N/A physical interaction ComPPI
RPL28 FAT3 25348397 N/A physical interaction ComPPI
RPL28 SIPA1L2 25348397 N/A physical interaction ComPPI
RPL28 PUM3 25348397 N/A physical interaction ComPPI
RPL28 TRO 25348397 N/A physical interaction ComPPI
RPL28 KIAA0232 25348397 N/A physical interaction ComPPI
RPL28 CDC42BPA 25348397 N/A physical interaction ComPPI
RPL28 MC1R 25348397 N/A physical interaction ComPPI
RPL28 TUBB3 25348397 N/A physical interaction ComPPI
RPL28 IFFO1 25348397 N/A physical interaction ComPPI
RPL28 RRP8 25348397 N/A physical interaction ComPPI
RPL28 CELSR2 25348397 N/A physical interaction ComPPI
RPL28 FREM2 25348397 N/A physical interaction ComPPI
RPL28 RBM34 25348397 N/A physical interaction ComPPI
RPL28 PLCH1 25348397 N/A physical interaction ComPPI
RPL28 RPL4 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
RPL28 RPL26L1 25348397 N/A physical interaction ComPPI
RPL28 PPAN 25348397 N/A physical interaction ComPPI
RPL28 POLE2 25348397 N/A physical interaction ComPPI
RPL28 ZNF354A 25348397 N/A physical interaction ComPPI
RPL28 NSD2 25348397 N/A physical interaction ComPPI
RPL28 ZCCHC7 25348397 N/A physical interaction ComPPI
RPL28 C1QBP 25348397 N/A physical interaction ComPPI
RPL28 FTSJ3 25348397 N/A physical interaction ComPPI
RPL28 ZNF644 25348397 N/A physical interaction ComPPI
RPL28 BRIX1 25348397 N/A physical interaction ComPPI
RPL28 RPL32 25348397 N/A physical interaction ComPPI
RPL28 PTPRD 25348397 N/A physical interaction ComPPI
RPL28 RPL30 25348397 N/A physical interaction ComPPI
RPL28 RPL27 25348397 N/A physical interaction ComPPI
RPL28 TUBA4A 25348397 N/A physical interaction ComPPI
RPL28 DKC1 25348397 N/A physical interaction ComPPI
RPL28 RPL18 25348397 N/A physical interaction ComPPI
RPL28 ADGRV1 25348397 N/A physical interaction ComPPI
RPL28 RPL6 25348397 N/A physical interaction ComPPI
RPL28 ZNF184 25348397 N/A physical interaction ComPPI
RPL28 CENPU 25348397 N/A physical interaction ComPPI
RPL28 RBM28 25348397 N/A physical interaction ComPPI
RPL28 SDCBP 25348397 N/A physical interaction ComPPI
RPL28 RPL7A 25348397 N/A physical interaction ComPPI
RPL28 PEX14 25348397 N/A physical interaction ComPPI
RPL28 ZNF865 25348397 N/A physical interaction ComPPI
RPL28 KLHL15 25348397 N/A physical interaction ComPPI
RPL28 RPS8 25348397 N/A physical interaction ComPPI
RPL28 NCL 25348397 N/A physical interaction ComPPI
RPL28 CYLD 25348397 N/A physical interaction ComPPI
RPL28 COX15 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL28 DNM1L 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL28 PDHA1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL28 SOAT1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL28 VDAC1 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
RPL28 FOXA1 25348397 N/A physical interaction ComPPI
RPL28 TRIM25 25348397 N/A physical interaction ComPPI
RPL28 MTF1 25348397 N/A physical interaction ComPPI
RPL28 CFTR 25348397 N/A physical interaction ComPPI
RPL28 STAU1 14525934 15121898 24234451 25348397 association experimental interaction detection,tandem affinity purification ComPPI,HPRD,IntAct
RPL28 RTCA 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL28 PSTPIP1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
RPL28 AGO1 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL28 AGO2 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL28 UBE2D3 19549727 24234451 25348397 physical association two hybrid ComPPI,IntAct
RPL28 GABARAP 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL28 VCAM1 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
RPL28 RRP1B 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RPL28 ZC3H18 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
RPS25 RPL28 25348397 N/A physical interaction ComPPI
RPL23 RPL28 25348397 N/A physical interaction ComPPI
RPL14 RPL28 25348397 N/A physical interaction ComPPI
EIF4A3 RPL28 23084401 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPS14 RPL28 25348397 N/A physical interaction ComPPI
LYAR RPL28 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
MAGEB2 RPL28 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
DL RPL28 25348397 N/A physical interaction ComPPI
RPL28 RAF 25348397 N/A physical interaction ComPPI
RPL28 MYC 25348397 N/A physical interaction ComPPI
RPL28 DSOR1 25348397 N/A physical interaction ComPPI
RPL28 PDK1 25348397 N/A physical interaction ComPPI
SGO1 RPL28 14525934 16541025 N/A experimental interaction detection HPRD
INAVA RPL28 24234451 29420262 association anti tag coimmunoprecipitation IntAct
MAPT RPL28 24234451 26402096 association,physical association anti bait coimmunoprecipitation IntAct
SRP14 RPL28 24234451 30021884 physical association cross-linking study IntAct
L1TD1 RPL28 24234451 25702638 association anti bait coimmunoprecipitation IntAct

Visualization










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