GENE：AHDC1
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | AHDC1 |
| FullNmae | AT-hook DNA binding motif containing 1 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:25230 |
| EnsembleID | ENSG00000126705 |
| Uniprot | Q5TGY3 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| AHDC1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| AHDC1 | GO:0001707,GO:0003700,GO:0005515,GO:0005634,GO:0005694,GO:0006355,GO:0030154,GO:0043589,GO:0140585 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | AHDC1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | AHDC1 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | AHDC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | AHDC1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| YBX1 | AHDC1 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | AHDC1 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F1 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXP1 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| TP53 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | AHDC1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00000AA464 | AHDC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00005651EE | AHDC1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000006FDD4 | AHDC1 | 22473208 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001C770D | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00004F2EB0 | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C4DB5 | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00001799A3 | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00002152A8 | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS0000364FEF | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075A760 | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BE495 | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000032D69B | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000075D15B | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| URS000019D79B | AHDC1 | 25416803 26701625 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ATXN1 | AHDC1 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| CBX1 | AHDC1 | 24234451 25348397 27705803 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| HNRNPL | AHDC1 | 25348397 | N/A | physical interaction | ComPPI |
| CBX5 | AHDC1 | 20562864 24234451 25348397 27705803 | association | anti tag coimmunoprecipitation,physical interaction,tandem affinity purification | ComPPI,IntAct |
| ZDHHC17 | AHDC1 | 24234451 24705354 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| H3-4 | AHDC1 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | AHDC1 | 25348397 | N/A | physical interaction | ComPPI |
| AHDC1 | ITSN2 | 25348397 | N/A | physical interaction | ComPPI |
| AHDC1 | APP | 25348397 | N/A | physical interaction | ComPPI |
| AHDC1 | CBX6 | 21282530 24234451 25348397 | association | physical interaction,tandem affinity purification | ComPPI,IntAct |
| AHDC1 | FBL | 25348397 | N/A | physical interaction | ComPPI |
| AHDC1 | DOK5 | 25348397 | N/A | physical interaction | ComPPI |
| AHDC1 | MYH9 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| AHDC1 | TRIM68 | 25348397 | N/A | physical interaction | ComPPI |
| AHDC1 | CBX3 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| AHDC1 | LRRK2 | 24234451 25348397 29513927 | N/A | protein array | ComPPI,IntAct |
| AHDC1 | DAPK1 | 24234451 25348397 29513927 | N/A | protein array | ComPPI,IntAct |