GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
LONP2 |
| FullNmae |
lon peptidase 2, peroxisomal |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:20598 |
| EnsembleID |
ENSG00000102910 |
| Uniprot |
Q86WA8 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| LONP2 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| LONP2 |
GO:0002020,GO:0004176,GO:0004252,GO:0005515,GO:0005524,GO:0005634,GO:0005777,GO:0005782,GO:0005782,GO:0005829,GO:0006515,GO:0006625,GO:0006625,GO:0007031,GO:0008233,GO:0014070,GO:0016020,GO:0016485,GO:0016485,GO:0016558,GO:0016887,GO:0019899,GO:0031998 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| AR |
LONP2 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| ETS1 |
LONP2 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
| SMARCA4 |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| GATA2 |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
LONP2 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000338542 |
LONP2 |
18668040
25416803
|
mrna cleavage,inhibition |
experimental interaction detection |
TarBase |
| URS000017EA6A |
LONP2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS0000137EDE |
LONP2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00000AA464 |
LONP2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00003CF1AD |
LONP2 |
23622248
25416803
|
mrna cleavage,inhibition |
clash |
TarBase |
| URS00004C5774 |
LONP2 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000096022 |
LONP2 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000753AD |
LONP2 |
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000043C1C3 |
LONP2 |
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000475586 |
LONP2 |
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| AMOT |
LONP2 |
19615732
24234451
25348397
|
physical association |
anti tag coimmunoprecipitation,physical interaction |
ComPPI,IntAct |
| CDC16 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| MAPK6 |
LONP2 |
24234451
25348397
26972000
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| WWOX |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PEX14 |
LONP2 |
22002062
24234451
25348397
|
colocalization |
confocal microscopy |
ComPPI,IntAct |
| OS9 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TRIM25 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| ELAVL1 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| RB1CC1 |
LONP2 |
20562859
24234451
25348397
|
association |
anti tag coimmunoprecipitation |
ComPPI,IntAct |
| FBXW11 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| IL17A |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| CAT |
LONP2 |
24234451
25348397
29568061
|
association |
pull down,proximity-dependent biotin identification |
ComPPI,IntAct |
| IL1R2 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| DCN |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| PEX5 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| TMOD3 |
LONP2 |
25348397
|
N/A |
physical interaction |
ComPPI |
| LONP2 |
SYCE1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
| MKI67 |
LONP2 |
24234451
26949251
|
association |
anti tag coimmunoprecipitation |
IntAct |
Visualization