Gene Information gene info

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GENE：PGLS

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PGLS
FullNmae 6-phosphogluconolactonase
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8903
EnsembleID ENSG00000130313
Uniprot O95336

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PGLS ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PGLS GO:0005515,GO:0005829,GO:0005829,GO:0005975,GO:0006098,GO:0006098,GO:0009051,GO:0017057,GO:0017057,GO:0017057,GO:0070062

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PGLS hsa:25796 path:hsa00030 Pentose phosphate pathway - Homo sapiens (human)
PGLS hsa:25796 path:hsa01100 Metabolic pathways - Homo sapiens (human)
PGLS hsa:25796 path:hsa01200 Carbon metabolism - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PGLS MDFI 16189514 23180781 physical association pull down InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PGLS 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PGLS 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF PGLS 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000042B108 PGLS 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001B0D1E PGLS 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 PGLS 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 PGLS 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBPMS PGLS 25348397 N/A physical interaction ComPPI
KRTAP5-9 PGLS 25348397 N/A physical interaction ComPPI
KRTAP10-8 PGLS 25348397 N/A physical interaction ComPPI
SSNA1 PGLS 25348397 N/A physical interaction ComPPI
KRTAP4-2 PGLS 25348397 N/A physical interaction ComPPI
KRT31 PGLS 25348397 N/A physical interaction ComPPI
KRT40 PGLS 25348397 N/A physical interaction ComPPI
DDIT4L PGLS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
MDFI PGLS 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
BLMH PGLS 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLSCR1 PGLS 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
NTRK1 PGLS 25348397 N/A physical interaction ComPPI
PEBP1 PGLS 25348397 N/A physical interaction ComPPI
EWSR1 PGLS 14525934 16189514 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RCHY1 PGLS 25348397 N/A physical interaction ComPPI
TERF1 PGLS 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
POT1 PGLS 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
IMPA1 PGLS 25348397 N/A physical interaction ComPPI
TERF2IP PGLS 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
TALDO1 PGLS 25348397 N/A physical interaction ComPPI
PGLS KRTAP10-9 25348397 N/A physical interaction ComPPI
PGLS KRTAP10-3 25348397 N/A physical interaction ComPPI
PGLS NOTCH2NLA 25348397 N/A physical interaction ComPPI
PGLS IMPA2 25348397 N/A physical interaction ComPPI
PGLS KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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