Gene Information gene info

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GENE：EIF5B

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EIF5B
FullNmae eukaryotic translation initiation factor 5B
LocusType gene with protein product
Status Approved
HGNC_id HGNC:30793
EnsembleID ENSG00000158417
Uniprot O60841

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EIF5B ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EIF5B GO:0000049,GO:0003723,GO:0003743,GO:0003743,GO:0003743,GO:0003924,GO:0003924,GO:0005515,GO:0005525,GO:0005737,GO:0005737,GO:0005829,GO:0006413,GO:0006446,GO:0006446,GO:0042255,GO:0045202,GO:0046872

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR EIF5B 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 EIF5B 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 EIF5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EIF5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EIF5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EIF5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EIF5B 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE EIF5B 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C EIF5B 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
SNRPB2 EIF5B 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
SNW1 EIF5B 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CDC5L EIF5B 20467437 24234451 25348397 association anti bait coimmunoprecipitation ComPPI,IntAct
CALM1 EIF5B 25348397 N/A physical interaction,inference by socio-affinity scoring ComPPI
EIF5B CBL 14525934 25348397 8621719 N/A experimental interaction detection,in vivo ComPPI,HPRD
EIF5B EIF1AX 12514125 14525934 25348397 N/A two hybrid,experimental interaction detection,in vitro,in vivo,two hybrid ComPPI,HPRD
EIF5B PRKAA1 20562859 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF5B POU5F1 25348397 N/A physical interaction ComPPI
EIF5B HDGF 21907836 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF5B SIRT7 25348397 N/A physical interaction ComPPI
EIF5B CAND1 25348397 N/A physical interaction ComPPI
EIF5B EIF3C 25348397 N/A physical interaction ComPPI
EIF5B BRCA1 25348397 N/A physical interaction ComPPI
EIF5B ECT2 25348397 N/A physical interaction ComPPI
EIF5B PAXIP1 25348397 N/A physical interaction ComPPI
EIF5B FN1 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
EIF5B CSNK2A1 22113938 24234451 25348397 phosphorylation reaction physical interaction,protein kinase assay ComPPI,IntAct
EIF5B MMS19 25348397 N/A physical interaction ComPPI
EIF5B ETS1 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
EIF5B YBX3 25348397 N/A physical interaction ComPPI
EIF5B TP53 25348397 N/A physical interaction ComPPI
EIF5B TFCP2 25348397 N/A physical interaction ComPPI
EIF5B OBSL1 25348397 N/A physical interaction ComPPI
EIF5B RHOJ 25348397 N/A physical interaction ComPPI
EIF5B DEGS1 25348397 N/A physical interaction ComPPI
EIF5B PLK2 25348397 N/A physical interaction ComPPI
EIF5B ABCF2 25348397 N/A physical interaction ComPPI
EIF5B DKC1 25348397 N/A physical interaction ComPPI
EIF5B FTSJ3 25348397 N/A physical interaction ComPPI
EIF5B NCL 25348397 N/A physical interaction ComPPI
EIF5B PIAS4 25348397 N/A physical interaction ComPPI
EIF5B RPLP0 25348397 N/A physical interaction ComPPI
EIF5B RPS6 25348397 N/A physical interaction ComPPI
EIF5B RRP12 25348397 N/A physical interaction ComPPI
EIF5B UBR4 25348397 N/A physical interaction ComPPI
EIF5B NOP53 25348397 N/A physical interaction ComPPI
EIF5B NHP2 25348397 N/A physical interaction ComPPI
EIF5B PTMA 25348397 N/A physical interaction ComPPI
EIF5B TSSC4 25348397 N/A physical interaction ComPPI
EIF5B SFN 25348397 N/A physical interaction ComPPI
EIF5B NTRK1 25348397 N/A physical interaction ComPPI
EIF5B XPO1 25348397 N/A physical interaction ComPPI
EIF5B XRCC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF5B FOXK2 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
EIF5B EGFR 25348397 N/A physical interaction ComPPI
EIF5B CDC42SE1 25348397 N/A physical interaction ComPPI
EIF5B MTUS2 25348397 N/A physical interaction ComPPI
EIF5B GTF2E2 25348397 N/A physical interaction ComPPI
EIF5B PA2G4 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B TRAP1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B SND1 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B ANXA5 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B GPI 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B IDH2 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B PDIA3 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B UBE2N 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B MRPL12 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B SLC25A10 25348397 N/A physical interaction ComPPI
EIF5B ZNF207 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B CS 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B PYGL 24234451 25348397 physical association physical interaction,inference by socio-affinity scoring ComPPI,IntAct
EIF5B UBE2A 25348397 N/A physical interaction ComPPI
EIF5B MAPK13 19135240 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF5B NR3C1 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
EIF5B SMAD2 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
EIF5B BECN1 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF5B CBX1 21888893 24234451 25348397 association tandem affinity purification ComPPI,IntAct
EIF5B PIH1D1 24234451 24656813 25348397 physical association pull down ComPPI,IntAct
EIF5B JUN 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
EIF5B CALM2 24234451 physical association inference by socio-affinity scoring IntAct
EIF5B HMMR 24234451 30021884 physical association cross-linking study IntAct
EIF5B THRB 24234451 30021884 physical association cross-linking study IntAct
NUMA1 EIF5B 24234451 30021884 physical association cross-linking study IntAct

Visualization










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