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GENE：DIAPH2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DIAPH2
FullNmae diaphanous related formin 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2877
EnsembleID ENSG00000147202
Uniprot O60879

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DIAPH2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DIAPH2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DIAPH2 GO:0003779,GO:0005102,GO:0005730,GO:0005769,GO:0005783,GO:0005829,GO:0005884,GO:0007292,GO:0030041,GO:0031267,GO:0043231,GO:0048477

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DIAPH2 hsa:1730 path:hsa04810 Regulation of actin cytoskeleton - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR DIAPH2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 DIAPH2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 DIAPH2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 DIAPH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004AC389 DIAPH2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002075FA DIAPH2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001F8FF2 DIAPH2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F DIAPH2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS00003003B4 DIAPH2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000000E601 DIAPH2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C DIAPH2 22012620 25416803 mrna cleavage,inhibition clip TarBase
URS000039D790 DIAPH2 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RHOD DIAPH2 25361965 interaction type N/A PTMCode2
DIAPH2 RHOD 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CDC42 DIAPH2 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
APBB1 DIAPH2 25348397 N/A physical interaction ComPPI
NCKIPSD DIAPH2 11509578 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
TCERG1 DIAPH2 25348397 N/A physical interaction ComPPI
RHOD DIAPH2 12577064 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
DIAPH2 CENPA 14525934 15085137 25348397 N/A two hybrid,experimental interaction detection,in vivo,two hybrid ComPPI,HPRD
DIAPH2 TENT4B 25348397 N/A physical interaction ComPPI
POLR1A DIAPH2 25348397 N/A physical interaction ComPPI
AURKB DIAPH2 21397845 27898060 stimulant N/A OmniPath

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