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GENE：PURA

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PURA
FullNmae purine rich element binding protein A
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9701
EnsembleID ENSG00000185129
Uniprot Q00577

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PURA ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PURA GO:0000122,GO:0000781,GO:0000900,GO:0000977,GO:0000981,GO:0003691,GO:0003697,GO:0003723,GO:0005515,GO:0005634,GO:0005634,GO:0006268,GO:0006270,GO:0006357,GO:0007399,GO:0008284,GO:0017148,GO:0032422,GO:0032839,GO:0043025,GO:0046332,GO:0046651,GO:0050673,GO:0098794,GO:0098963,GO:0098978,GO:0140297,GO:0140416

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ITGAX PURA 11937543 23180781 physical association electrophoretic mobility supershift assay InnateDB
EGR1 PURA 16741963 23180781 physical association anti tag coimmunoprecipitation InnateDB
EIF2AK2 PURA 21903422 23180781 physical association anti tag coimmunoprecipitation InnateDB
BMI1 PURA 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 PURA 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 PURA 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 PURA 18971253 trascriptional regulation,stimulation inferred by curator TFlink
IRF3 PURA 21062477 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000600E6 PURA 22835829 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000171CD1 PURA 22835829 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS000041CB9C PURA 22835829 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000042E1F PURA 22835829 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS00000DDD35 PURA 22835829 rna interference,inhibition miRNA interference luciferase reporter assay miRSponge
URS0000171CD1 PURA 22473208 22835829 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS000041CB9C PURA 22473208 22835829 25416803 mrna cleavage,inhibition clip,miRNA interference luciferase reporter assay TarBase
URS0000042E1F PURA 22835829 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000DDD35 PURA 22835829 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000600E6 PURA 22835829 25416803 mrna cleavage,inhibition miRNA interference luciferase reporter assay TarBase
URS00000B59A2 PURA 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000009262D PURA 18591254 25416803 mrna cleavage,inhibition array technology TarBase
URS00005651EE PURA 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000040EE1D PURA 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000345DEB PURA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001938D9 PURA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C04A2 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C28B2 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000016E46F PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004B83FE PURA 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 PURA 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 PURA 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 PURA 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 PURA 23446348 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000015188E PURA 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 PURA 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PURA 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000B7E30 PURA 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F PURA 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 PURA 20371350 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 PURA 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 PURA 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002F5FEE PURA 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 PURA 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003A5E54 PURA 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000075E2C3 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000122ED0 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002F8148 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000003575B PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FFA8C PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 PURA 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003804D8 PURA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS00000F31F4 PURA 19536157 25416803 mrna cleavage,inhibition clip TarBase
URS000008F0CF PURA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000427B68 PURA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000001A7A PURA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000202460 PURA 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000045B99E PURA 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK5 PURA 25361965 interaction type N/A PTMCode2
PURA CDK5 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SNW1 PURA 20467437 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
GABARAPL2 PURA 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
BMI1 PURA 25348397 N/A physical interaction ComPPI
RRS1 PURA 25348397 N/A physical interaction ComPPI
SP1 PURA 10457364 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
JUN PURA 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
RB1 PURA 14525934 24234451 25348397 27898060 7592647 physical association anti bait coimmunoprecipitation,experimental interaction detection,pull down,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
POLA1 PURA 25348397 N/A physical interaction ComPPI
CUL3 PURA 25348397 N/A physical interaction ComPPI
UBC PURA 25348397 N/A physical interaction ComPPI
NTRK1 PURA 25348397 N/A physical interaction ComPPI
YBX1 PURA 10318844 11751932 14525934 25348397 27898060 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
EIF2AK2 PURA 21903422 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
E2F1 PURA 10597240 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RFC2 PURA 25348397 N/A physical interaction ComPPI
PPP1CA PURA 24234451 25348397 25593058 association anti bait coimmunoprecipitation ComPPI,IntAct
HNRNPL PURA 25348397 N/A physical interaction ComPPI
ADAP1 PURA 12565890 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
CUL1 PURA 25348397 N/A physical interaction ComPPI
H1-4 PURA 25348397 N/A physical interaction ComPPI
RAB11A PURA 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
RAF1 PURA 25348397 N/A physical interaction ComPPI
PURA CCNT1 11730934 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
PURA PURB 10318844 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
PURA CDK5 12972605 14525934 25348397 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
PURA CNBP 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
PURA HNRNPA1 25348397 N/A physical interaction ComPPI
PURA MEPCE 25348397 N/A physical interaction ComPPI
PURA POU5F1 25348397 N/A physical interaction ComPPI
PURA CAND1 25348397 N/A physical interaction ComPPI
PURA ZNF638 25348397 N/A physical interaction ComPPI
PURA RFC3 25348397 N/A physical interaction ComPPI
PURA DDX23 25348397 N/A physical interaction ComPPI
PURA IL7R 25348397 N/A physical interaction ComPPI
PURA IGSF8 25348397 N/A physical interaction ComPPI
PURA ICAM1 25348397 N/A physical interaction ComPPI
PURA TARDBP 25348397 N/A physical interaction ComPPI
PURA LIN28A 25348397 N/A physical interaction ComPPI
PURA LIN28B 25348397 N/A physical interaction ComPPI
PURA SURF2 25348397 N/A physical interaction ComPPI
PURA ZC3H3 25348397 N/A physical interaction ComPPI
PURA RPS8 25348397 N/A physical interaction ComPPI
PURA PRR11 25348397 N/A physical interaction ComPPI
PURA WDR46 25348397 N/A physical interaction ComPPI
PURA ZCRB1 25348397 N/A physical interaction ComPPI
PURA G3BP1 25348397 N/A physical interaction ComPPI
PURA ESR2 21182203 24234451 25348397 association cosedimentation through density gradient ComPPI,IntAct
PURA MAP1LC3A 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
PURA PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
MKI67 PURA 24234451 26949251 association anti tag coimmunoprecipitation IntAct

Visualization










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