Gene Information gene info

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GENE：NDE1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol NDE1
FullNmae nudE neurodevelopment protein 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:17619
EnsembleID ENSG00000072864
Uniprot Q9NXR1

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
NDE1 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
NDE1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
NDE1 GO:0000132,GO:0000132,GO:0000776,GO:0000776,GO:0001764,GO:0005515,GO:0005813,GO:0005813,GO:0005829,GO:0005871,GO:0005874,GO:0007020,GO:0007059,GO:0007100,GO:0007405,GO:0008017,GO:0008017,GO:0016020,GO:0016477,GO:0021987,GO:0031616,GO:0032154,GO:0042802,GO:0045202,GO:0047496,GO:0051298,GO:0051301,GO:0051303,GO:0051303,GO:0051642

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 NDE1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 NDE1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 NDE1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 NDE1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 NDE1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 NDE1 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS0000065D58 NDE1 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000070B1D NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000BE495 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004E008F NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000013DD8 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016C318 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000451A1 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000157026 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000C85B2 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000033B548 NDE1 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PRKACA NDE1 22135298 phosphorylation N/A PhosphoSite
CDK1 NDE1 22135298 phosphorylation N/A PhosphoSite
CDK2 NDE1 22135298 phosphorylation N/A PhosphoSite
CDK5 NDE1 22135298 phosphorylation N/A PhosphoSite
YWHAG NDE1 25361965 interaction type N/A PTMCode2
NDE1 YWHAG 25361965 interaction type N/A PTMCode2
NDE1 PCNT 25361965 interaction type N/A PTMCode2
PCNT NDE1 25361965 interaction type N/A PTMCode2
NDE1 PAFAH1B1 25361965 interaction type N/A PTMCode2
PAFAH1B1 NDE1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TEKT4 NDE1 25348397 N/A physical interaction ComPPI
GOLGA2 NDE1 25348397 N/A physical interaction ComPPI
NDC80 NDE1 25348397 N/A physical interaction ComPPI
STX11 NDE1 25348397 N/A physical interaction ComPPI
SNAP29 NDE1 25348397 N/A physical interaction ComPPI
LZTS2 NDE1 25348397 N/A physical interaction ComPPI
YWHAG NDE1 14525934 15324660 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MKRN3 NDE1 25348397 N/A physical interaction ComPPI
JUNB NDE1 25348397 N/A physical interaction ComPPI
BORCS6 NDE1 25348397 N/A physical interaction ComPPI
FAM167A NDE1 25348397 N/A physical interaction ComPPI
EGLN3 NDE1 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct
MAPK1 NDE1 12556484 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
REL NDE1 25348397 N/A physical interaction ComPPI
AR NDE1 25348397 N/A physical interaction ComPPI
YWHAZ NDE1 25348397 N/A pull down ComPPI
TUBG1 NDE1 11163258 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
NDE1 PAFAH1B1 11163258 14525934 24234451 25348397 27173435 association,physical association two hybrid,experimental interaction detection,physical interaction,in vivo,tandem affinity purification,inference by socio-affinity scoring,two hybrid ComPPI,HPRD,IntAct
NDE1 ZNF365 25348397 N/A two hybrid,in vivo ComPPI
NDE1 DISC1 25348397 N/A physical interaction ComPPI
NDE1 NDEL1 22843697 24234451 25348397 physical association cross-linking study,physical interaction ComPPI,IntAct
NDE1 ARNT2 25348397 N/A physical interaction ComPPI
NDE1 TSPOAP1 25348397 N/A physical interaction ComPPI
NDE1 FAM9B 25348397 N/A physical interaction ComPPI
NDE1 HOXA2 25348397 N/A physical interaction ComPPI
NDE1 MED4 25348397 N/A physical interaction ComPPI
NDE1 TFIP11 25348397 N/A physical interaction ComPPI
NDE1 TRIM27 25348397 N/A physical interaction ComPPI
NDE1 UBQLN1 25348397 N/A physical interaction ComPPI
NDE1 USHBP1 25348397 N/A physical interaction ComPPI
NDE1 WAC 25348397 N/A physical interaction ComPPI
NDE1 ZNF398 25348397 N/A physical interaction ComPPI
NDE1 CEP250 25348397 N/A physical interaction ComPPI
NDE1 MOV10 25348397 N/A physical interaction ComPPI
NDE1 NXF1 25348397 N/A physical interaction ComPPI
NDE1 CCDC183 25348397 N/A physical interaction ComPPI
NDE1 EIF3F 25348397 N/A physical interaction ComPPI
NDE1 CHIA 25348397 N/A physical interaction ComPPI
NDE1 TSNARE1 25348397 N/A physical interaction ComPPI
NDE1 TCL1B 25348397 N/A physical interaction ComPPI
NDE1 OFD1 24234451 25348397 26638075 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDE1 CEP128 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDE1 CEP135 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
NDE1 XPO1 25348397 N/A physical interaction ComPPI
NDE1 DCAF13 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDE1 APIP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDE1 AMZ2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NDE1 CLPTM1L 25348397 N/A physical interaction ComPPI
NDE1 LCOR 25348397 N/A physical interaction ComPPI
NDE1 NUP54 25348397 N/A physical interaction ComPPI
NDE1 CCSER1 25348397 N/A physical interaction ComPPI
NDE1 CGNL1 25348397 N/A physical interaction ComPPI
NDE1 ARC 25348397 N/A physical interaction ComPPI
NDE1 TCP10L 25348397 N/A physical interaction ComPPI
NDE1 ZNF365 14525934 16682949 24234451 25348397 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct
NDE1 CDK1 12556484 14525934 16682949 24234451 25348397 phosphorylation reaction experimental interaction detection,in-gel kinase assay ComPPI,HPRD,IntAct
NDE1 CENPF 17600710 24234451 25348397 physical association pull down ComPPI,IntAct
NDE1 PLEKHA7 25348397 N/A anti bait coimmunoprecipitation ComPPI
YWHAQ NDE1 25348397 N/A physical interaction ComPPI
CSNK2A2 NDE1 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
TTC1 NDE1 25348397 N/A physical interaction ComPPI
HSCB NDE1 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
NDE1 NDE1 22843697 24234451 physical association cross-linking study,light scattering,molecular sieving,comigration in sds page IntAct
CDK5 NDE1 16682949 26206584 27898060 N/A N/A OmniPath
PRKACA NDE1 21677187 27898060 stimulant N/A OmniPath
CDK1 NDE1 12556484 16682949 18669648 20068231 27898060 stimulant N/A OmniPath
MAPK1 NDE1 12556484 18669648 20068231 27898060 stimulant N/A OmniPath
ZDHHC2 NDE1 19927128 27898060 N/A N/A OmniPath

Visualization










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