GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
RPAP1
FullNmae
RNA polymerase II associated protein 1
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:24567
EnsembleID
ENSG00000103932
Uniprot
Q9BWH6
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
RPAP1
ferroptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
RPAP1
cuproptosis
36010978
Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1.
Cuproptosis-related genes
Go Annotation:
GeneSymbol
Go id
RPAP1
GO:0000428,GO:0003677,GO:0005515,GO:0005634,GO:0006366,GO:0016779
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
RPAP1
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
GATA1
RPAP1
19941826
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
GATA2
RPAP1
18971253
19941826
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
YBX1
RPAP1
19151767
trascriptional regulation,stimulation
chromatin immunoprecipitation assay
TFlink
CEBPA
RPAP1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
RPAP1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
RPAP1
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000338542
RPAP1
18668040
25416803
mrna cleavage,inhibition
experimental interaction detection
TarBase
URS0000122ED0
RPAP1
19088304
25416803
mrna cleavage,inhibition
array technology
TarBase
URS00001C3AC1
RPAP1
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00001A7F58
RPAP1
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000035CC3E
RPAP1
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS00003CF1AD
RPAP1
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS0000324096
RPAP1
23622248
25416803
mrna cleavage,inhibition
clash
TarBase
URS000009A9A2
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00002152A8
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000019907A
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000137EDE
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS0000519450
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00001597DC
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000075A760
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000035AC91
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS000075D15B
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00002A8BC6
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
URS00001DA458
RPAP1
25416803
26701625
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
RPAP1
POLR2B
25361965
interaction type
N/A
PTMCode2
POLR2B
RPAP1
25361965
interaction type
N/A
PTMCode2
Source
Target
Pmid
Interactiontype
Methods
Database
CIAO1
RPAP1
17353931
24234451
25348397
physical association
anti bait coimmunoprecipitation
ComPPI,IntAct
HSPA8
RPAP1
24234451
25348397
29568061
association
pull down,physical interaction,proximity-dependent biotin identification
ComPPI,IntAct
POLR2L
RPAP1
24234451
25348397
25416956
physical association
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid
ComPPI,IntAct
MAGEA6
RPAP1
17353931
24234451
25348397
physical association
anti bait coimmunoprecipitation
ComPPI,IntAct
LAGE3
RPAP1
25348397
N/A
physical interaction
ComPPI
ERBIN
RPAP1
25348397
N/A
physical interaction
ComPPI
PPP4C
RPAP1
17353931
24234451
25348397
physical association
anti bait coimmunoprecipitation
ComPPI,IntAct
MCM10
RPAP1
25348397
N/A
physical interaction
ComPPI
NTRK1
RPAP1
25348397
N/A
physical interaction
ComPPI
BAG6
RPAP1
25348397
N/A
physical interaction
ComPPI
ILK
RPAP1
17353931
24234451
25348397
physical association
anti bait coimmunoprecipitation
ComPPI,IntAct
XPO1
RPAP1
25348397
N/A
physical interaction
ComPPI
GPN1
RPAP1
25348397
N/A
physical interaction
ComPPI
IGBP1
RPAP1
25348397
N/A
physical interaction
ComPPI
SRP72
RPAP1
25348397
N/A
physical interaction
ComPPI
ELAVL1
RPAP1
25348397
N/A
physical interaction
ComPPI
POT1
RPAP1
21044950
24234451
25348397
physical association
pull down,physical interaction,bimolecular fluorescence complementation
ComPPI,IntAct
SNU13
RPAP1
25348397
N/A
physical interaction
ComPPI
TERF2IP
RPAP1
21044950
24234451
25348397
physical association
physical interaction,bimolecular fluorescence complementation
ComPPI,IntAct
POLR2J
RPAP1
25348397
N/A
physical interaction
ComPPI
POLR3A
RPAP1
25348397
N/A
physical interaction
ComPPI
HLTF
RPAP1
25348397
N/A
physical interaction
ComPPI
SYTL2
RPAP1
25348397
N/A
physical interaction
ComPPI
EFTUD2
RPAP1
25348397
N/A
physical interaction
ComPPI
POLR2C
RPAP1
25348397
N/A
physical interaction
ComPPI
CSNK2B
RPAP1
25348397
N/A
physical interaction
ComPPI
IPO9
RPAP1
25348397
N/A
physical interaction
ComPPI
KIF11
RPAP1
25348397
N/A
physical interaction
ComPPI
HSPD1
RPAP1
25348397
N/A
physical interaction
ComPPI
POLR2B
RPAP1
25348397
N/A
physical interaction
ComPPI
DDX3Y
RPAP1
25348397
N/A
physical interaction
ComPPI
ILF3
RPAP1
25348397
N/A
physical interaction
ComPPI
CENPC
RPAP1
25348397
N/A
physical interaction
ComPPI
HNRNPA1
RPAP1
25348397
N/A
physical interaction
ComPPI
C1ORF94
RPAP1
25348397
N/A
physical interaction
ComPPI
PAICS
RPAP1
25348397
N/A
physical interaction
ComPPI
PPIL3
RPAP1
25348397
N/A
physical interaction
ComPPI
NUMA1
RPAP1
25348397
N/A
physical interaction
ComPPI
CCT6A
RPAP1
25348397
N/A
physical interaction
ComPPI
MAGED2
RPAP1
25348397
N/A
physical interaction
ComPPI
IGF2BP1
RPAP1
25348397
N/A
physical interaction
ComPPI
ANAPC1
RPAP1
25348397
N/A
physical interaction
ComPPI
POLK
RPAP1
24234451
25348397
26496610
association
anti tag coimmunoprecipitation,physical interaction
ComPPI,IntAct
POLR1C
RPAP1
25348397
N/A
physical interaction
ComPPI
MYZAP
RPAP1
25348397
N/A
physical interaction
ComPPI
POLR2M
RPAP1
25348397
N/A
physical interaction
ComPPI
POLR3B
RPAP1
25348397
N/A
physical interaction
ComPPI
ZFR
RPAP1
25348397
N/A
physical interaction
ComPPI
MEPCE
RPAP1
25348397
N/A
physical interaction
ComPPI
RPAP1
ARHGAP23
25348397
N/A
physical interaction
ComPPI
RPAP1
PHF8
25348397
N/A
physical interaction
ComPPI
RPAP1
SLFN11
25348397
N/A
physical interaction
ComPPI
RPAP1
CCDC8
25348397
N/A
physical interaction
ComPPI
RPAP1
GPN2
25348397
N/A
physical interaction
ComPPI
STK38L
RPAP1
24234451
30108113
association
proximity-dependent biotin identification
IntAct
Visualization