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GENE：RPL27A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RPL27A
FullNmae ribosomal protein L27a
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10329
EnsembleID ENSG00000166441
Uniprot P46776

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RPL27A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RPL27A GO:0002181,GO:0002181,GO:0003723,GO:0003735,GO:0003735,GO:0003735,GO:0005515,GO:0005737,GO:0005783,GO:0005829,GO:0005829,GO:0006412,GO:0016020,GO:0022625,GO:0022625,GO:0022625,GO:0022625,GO:0022626

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RPL27A hsa:6157 path:hsa03010 Ribosome - Homo sapiens (human)
RPL27A hsa:6157 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ISG15 RPL27A 16009940 23180781 physical association unspecified method InnateDB
EED RPL27A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RNF2 RPL27A 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB
RPL27A UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 RPL27A 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
MYC RPL27A 12695333 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 RPL27A 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 RPL27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RPL27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RPL27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RPL27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RPL27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RPL27A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000079D48 RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C3AC1 RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C308D RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000AA464 RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00005651EE RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000041CB9C RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000000B1C9 RPL27A 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A4ABF RPL27A 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000002569A RPL27A 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001067D1 RPL27A 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001D6605 RPL27A 20371350 21572407 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D814 RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075CC78 RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00006DE17B RPL27A 23706177 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000001EB3 RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002AA55A RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000021202F RPL27A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 RPL27A 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A RPL27A 23706177 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA RPL27A 23706177 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CUL5 RPL27A 25348397 N/A physical interaction ComPPI
AIMP2 RPL27A 25348397 N/A physical interaction ComPPI
RPL9 RPL27A 25348397 N/A physical interaction ComPPI
RPS7 RPL27A 25348397 N/A physical interaction ComPPI
ISG15 RPL27A 25348397 N/A physical interaction ComPPI
NPM1 RPL27A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RPL37A RPL27A 25348397 N/A physical interaction ComPPI
UBL4A RPL27A 25348397 N/A physical interaction ComPPI
RPL11 RPL27A 25348397 N/A physical interaction ComPPI
RPL36AL RPL27A 25348397 N/A physical interaction ComPPI
RPS15 RPL27A 25348397 N/A physical interaction ComPPI
RPS26 RPL27A 25348397 N/A physical interaction ComPPI
KEAP1 RPL27A 25348397 N/A physical interaction ComPPI
MCM2 RPL27A 25348397 N/A physical interaction ComPPI
EXOSC1 RPL27A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
INO80B RPL27A 25348397 N/A physical interaction ComPPI
RACK1 RPL27A 25348397 N/A physical interaction ComPPI
PRKACB RPL27A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPL10A RPL27A 25348397 N/A physical interaction ComPPI
PAK1 RPL27A 25348397 N/A two hybrid,physical interaction ComPPI
RPL10 RPL27A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CD81 RPL27A 25348397 N/A physical interaction ComPPI
GRB2 RPL27A 12577067 24234451 25348397 association pull down ComPPI,IntAct
JUN RPL27A 24234451 25348397 25609649 association anti bait coimmunoprecipitation ComPPI,IntAct
GTF2F2 RPL27A 20195357 24234451 25348397 physical association display technology,physical interaction,tandem affinity purification ComPPI,IntAct
DHX9 RPL27A 25348397 N/A physical interaction ComPPI
COPS5 RPL27A 25348397 N/A physical interaction ComPPI
RBM39 RPL27A 25348397 N/A physical interaction ComPPI
RPL18A RPL27A 25348397 N/A physical interaction ComPPI
SIAH1 RPL27A 25348397 N/A physical interaction ComPPI
UBA52 RPL27A 25348397 N/A physical interaction ComPPI
PARP1 RPL27A 25348397 N/A physical interaction ComPPI
RPS3A RPL27A 25348397 N/A physical interaction ComPPI
HNRNPU RPL27A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
THOC5 RPL27A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EIF2S1 RPL27A 25348397 N/A physical interaction ComPPI
PABPC1 RPL27A 25348397 N/A physical interaction ComPPI
QARS1 RPL27A 25348397 N/A physical interaction ComPPI
RPS6 RPL27A 25348397 N/A physical interaction ComPPI
RPS25 RPL27A 25348397 N/A physical interaction ComPPI
HUWE1 RPL27A 25348397 N/A physical interaction ComPPI
RPS18 RPL27A 25348397 N/A physical interaction ComPPI
RPL12 RPL27A 25348397 N/A physical interaction ComPPI
RPS13 RPL27A 25348397 N/A physical interaction ComPPI
RPL4 RPL27A 25348397 N/A physical interaction ComPPI
RPLP0 RPL27A 25348397 N/A physical interaction ComPPI
RPLP2 RPL27A 25348397 N/A physical interaction ComPPI
RPLP1 RPL27A 25348397 N/A physical interaction ComPPI
HNRNPA2B1 RPL27A 25348397 N/A physical interaction ComPPI
CUL2 RPL27A 25348397 N/A physical interaction ComPPI
CUL4B RPL27A 25348397 N/A physical interaction ComPPI
MDM2 RPL27A 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CDK2 RPL27A 25348397 N/A physical interaction ComPPI
CUL1 RPL27A 25348397 N/A physical interaction ComPPI
RPL7A RPL27A 25348397 N/A physical interaction ComPPI
SFN RPL27A 25348397 N/A physical interaction ComPPI
RNF2 RPL27A 25348397 N/A physical interaction ComPPI
RIOX2 RPL27A 25348397 N/A x-ray crystallography,physical interaction ComPPI
PTEN RPL27A 25348397 N/A physical interaction ComPPI
MAP3K14 RPL27A 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
VCAM1 RPL27A 19738201 22623428 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
ITGA4 RPL27A 25348397 N/A physical interaction ComPPI
EED RPL27A 25348397 N/A physical interaction ComPPI
RPL7 RPL27A 25348397 N/A physical interaction ComPPI
CUL7 RPL27A 25348397 N/A physical interaction ComPPI
H3C1 RPL27A 25348397 N/A physical interaction ComPPI
CAND1 RPL27A 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
RPL5 RPL27A 25348397 N/A physical interaction ComPPI
MARS1 RPL27A 25348397 N/A physical interaction ComPPI
DUSP22 RPL27A 25348397 N/A physical interaction ComPPI
TRIM25 RPL27A 25348397 N/A physical interaction ComPPI
NOP56 RPL27A 25348397 N/A physical interaction ComPPI
ESR1 RPL27A 21182205 24234451 25348397 association affinity chromatography technology,cosedimentation through density gradient,physical interaction ComPPI,IntAct
BRCA1 RPL27A 25348397 N/A physical interaction ComPPI
PEX6 RPL27A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RPL6 RPL27A 25348397 N/A physical interaction ComPPI
RPL23A RPL27A 25348397 N/A physical interaction ComPPI
RPL13 RPL27A 25348397 N/A physical interaction ComPPI
RPL23 RPL27A 25348397 N/A physical interaction ComPPI
MAGOH RPL27A 25348397 N/A physical interaction ComPPI
RPS9 RPL27A 25348397 N/A physical interaction ComPPI
RPS10 RPL27A 25348397 N/A physical interaction ComPPI
RPS20 RPL27A 25348397 N/A physical interaction ComPPI
PAN2 RPL27A 25348397 N/A physical interaction ComPPI
RPL14 RPL27A 25348397 N/A physical interaction ComPPI
PES1 RPL27A 25348397 N/A physical interaction ComPPI
AGO2 RPL27A 17932509 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
AGO1 RPL27A 17932509 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
RRP1B RPL27A 20926688 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
EIF4A3 RPL27A 25348397 N/A physical interaction ComPPI
IGSF8 RPL27A 25348397 N/A physical interaction ComPPI
DARS1 RPL27A 25348397 N/A physical interaction ComPPI
RPSA RPL27A 25348397 N/A physical interaction ComPPI
EEF1E1 RPL27A 25348397 N/A physical interaction ComPPI
RPL24 RPL27A 25348397 N/A physical interaction ComPPI
ICAM1 RPL27A 25348397 N/A physical interaction ComPPI
RPS2 RPL27A 25348397 N/A physical interaction ComPPI
HNRNPA1 RPL27A 25348397 N/A physical interaction ComPPI
CYLD RPL27A 25348397 N/A physical interaction ComPPI
RPS14 RPL27A 25348397 N/A physical interaction ComPPI
RPS15A RPL27A 25348397 N/A physical interaction ComPPI
RPL31 RPL27A 25348397 N/A physical interaction ComPPI
RPL8 RPL27A 25348397 N/A physical interaction ComPPI
RPL36 RPL27A 25348397 N/A physical interaction ComPPI
RPL30 RPL27A 25348397 N/A physical interaction ComPPI
RPS11 RPL27A 25348397 N/A physical interaction ComPPI
FAU RPL27A 25348397 N/A physical interaction ComPPI
RPS4X RPL27A 25348397 N/A physical interaction ComPPI
RPL21 RPL27A 25348397 N/A physical interaction ComPPI
RPL35A RPL27A 25348397 N/A physical interaction ComPPI
RPL22 RPL27A 25348397 N/A physical interaction ComPPI
RPL17 RPL27A 25348397 N/A physical interaction ComPPI
RPS3 RPL27A 25348397 N/A physical interaction ComPPI
RPS27 RPL27A 25348397 N/A physical interaction ComPPI
ABCF1 RPL27A 25348397 N/A physical interaction ComPPI
RPL13A RPL27A 25348397 N/A physical interaction ComPPI
RPL15 RPL27A 25348397 N/A physical interaction ComPPI
RPL3 RPL27A 25348397 N/A physical interaction ComPPI
RPS16 RPL27A 25348397 N/A physical interaction ComPPI
HTR7 RPL27A 19486527 24234451 25348397 association tandem affinity purification ComPPI,IntAct
RPL38 RPL27A 25348397 N/A physical interaction ComPPI
NOM1 RPL27A 21576267 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
FN1 RPL27A 19738201 24234451 25348397 association cross-linking study,physical interaction ComPPI,IntAct
RANBP3 RPL27A 25348397 N/A physical interaction ComPPI
CCAR2 RPL27A 25348397 N/A physical interaction ComPPI
RPS19 RPL27A 25348397 N/A physical interaction ComPPI
RPL32 RPL27A 25348397 N/A physical interaction ComPPI
RPL34 RPL27A 25348397 N/A physical interaction ComPPI
RPL35 RPL27A 25348397 N/A physical interaction ComPPI
EBNA1BP2 RPL27A 25348397 N/A physical interaction ComPPI
NCL RPL27A 25348397 N/A physical interaction ComPPI
RPL18 RPL27A 25348397 N/A physical interaction ComPPI
AGO4 RPL27A 19167051 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
FAU RPL27A 25348397 N/A physical interaction ComPPI
RPLP0P6 RPL27A 25348397 N/A physical interaction ComPPI
AIMP1 RPL27A 25348397 N/A physical interaction ComPPI
RPL3L RPL27A 25348397 N/A physical interaction ComPPI
RPS12 RPL27A 25348397 N/A physical interaction ComPPI
NEPRO RPL27A 25348397 N/A physical interaction ComPPI
ZC3H18 RPL27A 24234451 25348397 29298432 association anti tag coimmunoprecipitation ComPPI,IntAct
ZBTB1 RPL27A 25348397 N/A physical interaction ComPPI
RPS5 RPL27A 25348397 N/A physical interaction ComPPI
RPS27L RPL27A 25348397 N/A physical interaction ComPPI
RPS8 RPL27A 25348397 N/A physical interaction ComPPI
ZNF746 RPL27A 25348397 N/A physical interaction ComPPI
RPS23 RPL27A 25348397 N/A physical interaction ComPPI
RPL27A RPL19 25348397 N/A physical interaction ComPPI
RPL27A RPL10L 25348397 N/A physical interaction ComPPI
RPL27A LUZP4 25348397 N/A physical interaction ComPPI
RPL27A RPL26L1 25348397 N/A physical interaction ComPPI
RPL27A RPL27 25348397 N/A physical interaction ComPPI
RPL27A RC3H1 25348397 N/A physical interaction ComPPI
DUX4 RPL27A 24234451 25348397 26816005 association pull down ComPPI,IntAct
RAF RPL27A 25348397 N/A physical interaction ComPPI
RPL27A ACACA 24234451 30021884 physical association cross-linking study IntAct
RPL27A TRMT11 24234451 30021884 physical association cross-linking study IntAct
RPL27A CDKN1B 24234451 30021884 physical association cross-linking study IntAct
RPL27A EML5 24234451 30021884 physical association cross-linking study IntAct
L1TD1 RPL27A 24234451 25702638 association anti bait coimmunoprecipitation IntAct
TPT1 RPL27A 24234451 27607350 association anti bait coimmunoprecipitation IntAct
ISG15 RPL27A 16009940 27898060 N/A N/A OmniPath

Source Target Pmid Interactiontype Methods Database
URS00009B6D15 RPL27A 27087310 direct interaction,inhibition N/A NPInter

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