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GENE：SCYL3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SCYL3
FullNmae SCY1 like pseudokinase 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:19285
EnsembleID ENSG00000000457
Uniprot Q8IZE3

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SCYL3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SCYL3 GO:0000139,GO:0005515,GO:0005524,GO:0005737,GO:0005783,GO:0005794,GO:0005829,GO:0006954,GO:0008104,GO:0016477,GO:0021522,GO:0030027,GO:0042802,GO:0048666

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SCYL3 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
E2F4 SCYL3 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 SCYL3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 SCYL3 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
YBX1 SCYL3 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SCYL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SCYL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 SCYL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SCYL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SCYL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SCYL3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001C770D SCYL3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EEE35 SCYL3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 SCYL3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000FC8EB SCYL3 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS00003AA845 SCYL3 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS00002C0FCB SCYL3 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS000001C659 SCYL3 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000482389 SCYL3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040828B SCYL3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5E03 SCYL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000045DBD SCYL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000508C13 SCYL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005D986D SCYL3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005586D0 SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001C85C7 SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001E0AEA SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003D8730 SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003E5ECC SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS000025EABA SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00002B0B46 SCYL3 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
EZR SCYL3 25361965 interaction type N/A PTMCode2
SCYL3 EZR 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
TXN2 SCYL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CEP19 SCYL3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
KEAP1 SCYL3 25348397 N/A physical interaction ComPPI
CD44 SCYL3 12651155 24234451 25348397 physical association confocal microscopy ComPPI,IntAct
XPO1 SCYL3 25348397 N/A physical interaction ComPPI
HDAC11 SCYL3 25348397 N/A physical interaction ComPPI
TGOLN2 SCYL3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
BET1 SCYL3 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EZR SCYL3 12651155 14525934 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vivo,confocal microscopy ComPPI,HPRD,IntAct
GABARAPL1 SCYL3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SCYL3 LHX8 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SCYL3 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SCYL3 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SCYL3 TPTE 25348397 N/A physical interaction ComPPI
ITGB1 SCYL3 24234451 30021884 physical association cross-linking study IntAct

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