GENE：ZHX3
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | ZHX3 |
| FullNmae | zinc fingers and homeoboxes 3 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:15935 |
| EnsembleID | ENSG00000174306 |
| Uniprot | Q9H4I2 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| ZHX3 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| ZHX3 | autosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| ZHX3 | GO:0000785,GO:0000981,GO:0000981,GO:0003677,GO:0003700,GO:0005515,GO:0005634,GO:0005634,GO:0005654,GO:0006357,GO:0030154,GO:0042803,GO:0045669,GO:0045892,GO:0046872,GO:0046982 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| AR | ZHX3 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
| ETS1 | ZHX3 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA1 | ZHX3 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| GATA2 | ZHX3 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| YBX1 | ZHX3 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| PRDM14 | ZHX3 | 18971253 20953172 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| HNF4A | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| SPI1 | ZHX3 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS0000070B1D | ZHX3 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000031F6C2 | ZHX3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001A405B | ZHX3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000D2680 | ZHX3 | 22100165 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00001CF056 | ZHX3 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
| URS0000427B68 | ZHX3 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004719AB | ZHX3 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000B7E30 | ZHX3 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000028DE3F | ZHX3 | 21572407 25416803 | mrna cleavage,inhibition | clip,clip | TarBase |
| URS00002233F4 | ZHX3 | 20371350 21572407 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004977C5 | ZHX3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000016FD1A | ZHX3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000021D7C8 | ZHX3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000003575B | ZHX3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000048BA36 | ZHX3 | 19536157 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| TFAP4 | ZHX3 | 25348397 | N/A | physical interaction | ComPPI |
| ATXN1 | ZHX3 | 14525934 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid | ComPPI,HPRD,IntAct |
| NLK | ZHX3 | 21516116 24234451 25348397 25416956 | physical association | two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
| NFYA | ZHX3 | 12659632 14525934 25348397 | N/A | two hybrid,two hybrid | ComPPI,HPRD |
| PDIA6 | ZHX3 | 25348397 | N/A | physical interaction | ComPPI |
| EWSR1 | ZHX3 | 25348397 | N/A | physical interaction | ComPPI |
| ZHX1 | ZHX3 | 12659632 14525934 25348397 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD |
| ZHX3 | ZHX2 | 14525934 14659886 25348397 27898060 | N/A | two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid | ComPPI,HPRD,OmniPath |
| ZHX3 | SH2D2A | 25348397 | N/A | physical interaction | ComPPI |
| ZHX3 | NTAQ1 | 25348397 | N/A | physical interaction | ComPPI |
| ZHX3 | ZHX3 | 12659632 14525934 | N/A | experimental interaction detection,two hybrid | HPRD |
| RPL7A | ZHX3 | 24234451 30021884 | physical association | cross-linking study | IntAct |