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GENE：PRRC2C

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PRRC2C
FullNmae proline rich coiled-coil 2C
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24903
EnsembleID ENSG00000117523
Uniprot Q9Y520

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PRRC2C ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PRRC2C GO:0002244,GO:0003723,GO:0005515,GO:0005829,GO:0010494,GO:0016020,GO:0034063

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRRC2C UBB 23180781 24816145 ubiquitination reaction ubiquitinase assay InnateDB

Source Target Pmid Interactiontype Methods Database
AR PRRC2C 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 PRRC2C 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PRRC2C 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 PRRC2C 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 PRRC2C 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 PRRC2C 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000070B1D PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000005481D PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A405B PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000042E1F PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000006FDD4 PRRC2C 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003A5E54 PRRC2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000018C928 PRRC2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000236310 PRRC2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000170CF4 PRRC2C 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000171CD1 PRRC2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C PRRC2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D PRRC2C 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 PRRC2C 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000427B68 PRRC2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004719AB PRRC2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002233F4 PRRC2C 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000157F5 PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000031E12 PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000029979D PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003D8730 PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000B7E30 PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005F305A PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000077AED PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004F507C PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000072B4C8 PRRC2C 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CHEK1 PRRC2C 22135298 phosphorylation N/A PhosphoSite
AURKB PRRC2C 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
HSPA8 PRRC2C 24234451 25348397 29568061 association pull down ComPPI,IntAct
RABGGTB PRRC2C 25348397 N/A physical interaction ComPPI
QPRT PRRC2C 25348397 N/A physical interaction ComPPI
PCBD1 PRRC2C 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
RPL10 PRRC2C 25348397 N/A physical interaction ComPPI
SNRNP70 PRRC2C 25348397 N/A physical interaction ComPPI
SFPQ PRRC2C 25348397 N/A physical interaction ComPPI
GSK3B PRRC2C 24234451 25348397 29568061 association pull down ComPPI,IntAct
NTRK1 PRRC2C 25348397 N/A physical interaction ComPPI
CANX PRRC2C 24234451 25348397 29568061 association pull down ComPPI,IntAct
CFTR PRRC2C 25348397 N/A physical interaction ComPPI
CSNK2A2 PRRC2C 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MDM2 PRRC2C 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
AURKA PRRC2C 25348397 N/A physical interaction ComPPI
TRPC4AP PRRC2C 25348397 N/A physical interaction ComPPI
VCAM1 PRRC2C 22623428 24234451 25348397 association cross-linking study ComPPI,IntAct
ITGA4 PRRC2C 25348397 N/A physical interaction ComPPI
PRKN PRRC2C 25348397 N/A physical interaction ComPPI
NR3C1 PRRC2C 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
SEM1 PRRC2C 24234451 24811749 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TRIM25 PRRC2C 25348397 N/A physical interaction ComPPI
ELAVL1 PRRC2C 25348397 N/A physical interaction ComPPI
SRPK2 PRRC2C 25348397 N/A physical interaction ComPPI
ESR2 PRRC2C 21182203 24234451 25348397 association affinity chromatography technology ComPPI,IntAct
AURKB PRRC2C 25348397 N/A physical interaction ComPPI
HINFP PRRC2C 25348397 N/A physical interaction ComPPI
TARDBP PRRC2C 25348397 N/A physical interaction ComPPI
CEP57 PRRC2C 25348397 N/A physical interaction ComPPI
CYLD PRRC2C 25348397 N/A physical interaction ComPPI
LCOR PRRC2C 25348397 N/A physical interaction ComPPI
CEP76 PRRC2C 25348397 N/A physical interaction ComPPI
GABARAPL1 PRRC2C 20562859 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
LGALS3BP PRRC2C 25348397 N/A physical interaction ComPPI
FBL PRRC2C 25348397 N/A physical interaction ComPPI
SIRT7 PRRC2C 25348397 N/A physical interaction ComPPI
PRMT8 PRRC2C 25348397 N/A physical interaction ComPPI
HAUS2 PRRC2C 25348397 N/A physical interaction ComPPI
FOXK2 PRRC2C 25348397 N/A physical interaction ComPPI
ATOH1 PRRC2C 25348397 N/A physical interaction ComPPI
TP53 PRRC2C 25348397 N/A physical interaction ComPPI
BCAR1 PRRC2C 24234451 25348397 28007913 association anti bait coimmunoprecipitation ComPPI,IntAct
SEM1 PRRC2C 25348397 N/A physical interaction ComPPI
G3BP1 PRRC2C 25348397 N/A physical interaction ComPPI
PRRC2C LGR4 25348397 N/A physical interaction ComPPI
PRRC2C ZFP41 25348397 N/A physical interaction ComPPI
PRRC2C JPH4 25348397 N/A physical interaction ComPPI
PRRC2C CHCHD10 25348397 N/A physical interaction ComPPI
HMGN3 PRRC2C 24234451 30021884 physical association cross-linking study IntAct
H3-4 PRRC2C 24234451 30021884 physical association cross-linking study IntAct
PRRC2C PPFIBP1 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009C3F6D PRRC2C 27087310 direct interaction,inhibition N/A NPInter

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