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GENE：CIR1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol CIR1
FullNmae corepressor interacting with RBPJ, CIR1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24217
EnsembleID ENSG00000138433
Uniprot Q86X95

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
CIR1 pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CIR1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CIR1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
CIR1 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
CIR1 GO:0000122,GO:0001701,GO:0003714,GO:0003714,GO:0005515,GO:0005634,GO:0005634,GO:0005737,GO:0005813,GO:0006397,GO:0008380,GO:0016607,GO:0019901,GO:0032991,GO:0042826,GO:0044877,GO:0045892,GO:0045892

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
CIR1 hsa:9541 path:hsa04330 Notch signaling pathway - Homo sapiens (human)
CIR1 hsa:9541 path:hsa05169 Epstein-Barr virus infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CIR1 NKAP 19409814 23180781 physical association anti tag coimmunoprecipitation InnateDB
RBPJ CIR1 19165418 23331499 9874765 stimulation N/A SignaLink

Source Target Pmid Interactiontype Methods Database
ETS1 CIR1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 CIR1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 CIR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF CIR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 CIR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS CIR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A CIR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
SNW1 CIR1 10644367 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vivo,two hybrid ComPPI,HPRD
CDCA3 CIR1 25348397 N/A physical interaction ComPPI
GCA CIR1 25348397 N/A physical interaction ComPPI
U2AF1L5 CIR1 25348397 N/A physical interaction ComPPI
CPNE1 CIR1 25348397 N/A physical interaction ComPPI
NCOR2 CIR1 25348397 N/A physical interaction,in vivo ComPPI
EPHA2 CIR1 25348397 N/A physical interaction ComPPI
SRSF1 CIR1 15652350 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
SRSF2 CIR1 14525934 15652350 24234451 25348397 3031469 colocalization,physical association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,fluorescence microscopy,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
HDAC2 CIR1 24234451 25348397 9874765 physical association two hybrid ComPPI,IntAct
TCEA1 CIR1 11591653 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
RP9 CIR1 25348397 N/A physical interaction ComPPI
SAP30 CIR1 14525934 24234451 25348397 9874765 physical association two hybrid,physical interaction,two hybrid ComPPI,HPRD,IntAct
CIR1 RBPJ 14525934 24234451 25348397 9874765 colocalization,physical association two hybrid,physical interaction,fluorescence microscopy,two hybrid ComPPI,HPRD,IntAct
CIR1 U2AF1 15652350 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,pull down,physical interaction ComPPI,IntAct
CIR1 NEK6 25348397 N/A physical interaction ComPPI
CIR1 CEP76 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
CIR1 FANCI 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CIR1 AGO3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CIR1 CCNYL1 25348397 N/A physical interaction ComPPI
CIR1 UBR3 25348397 N/A physical interaction ComPPI
CIR1 BTBD1 25348397 N/A physical interaction ComPPI
CIR1 DCAF10 25348397 N/A physical interaction ComPPI
CIR1 RBM12 25348397 N/A physical interaction ComPPI
CIR1 CTNNA2 25348397 N/A physical interaction ComPPI
CIR1 HDAC1 24234451 25348397 9874765 colocalization fluorescence microscopy ComPPI,IntAct
CIR1 NKAP 19409814 27898060 N/A N/A OmniPath
RBPJ CIR1 27898060 9874765 stimulant N/A OmniPath

Visualization










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