Gene Information gene info

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GENE：MS4A2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MS4A2
FullNmae membrane spanning 4-domains A2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7316
EnsembleID ENSG00000149534
Uniprot Q01362

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MS4A2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MS4A2 GO:0005515,GO:0005886,GO:0005886,GO:0005886,GO:0006955,GO:0007166,GO:0009897,GO:0019863,GO:0032998

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MS4A2 hsa:2206 path:hsa04071 Sphingolipid signaling pathway - Homo sapiens (human)
MS4A2 hsa:2206 path:hsa04072 Phospholipase D signaling pathway - Homo sapiens (human)
MS4A2 hsa:2206 path:hsa04664 Fc epsilon RI signaling pathway - Homo sapiens (human)
MS4A2 hsa:2206 path:hsa05310 Asthma - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
MS4A2 NFYC 16982898 23180781 physical association anti tag coimmunoprecipitation InnateDB
MS4A2 HDAC1 16982898 23180781 physical association anti tag coimmunoprecipitation InnateDB
MS4A2 HDAC2 16982898 23180781 physical association anti tag coimmunoprecipitation InnateDB
LYN MS4A2 22845063 23180781 physical association pull down InnateDB
GATA2 MS4A2 23180781 24639354 physical association anti tag coimmunoprecipitation InnateDB
GATA1 MS4A2 23180781 24639354 physical association anti tag coimmunoprecipitation InnateDB
SPI1 MS4A2 23180781 24639354 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
GRB2 MS4A2 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
GATA2 MS4A2 19941826 24639354 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
POU2F1 MS4A2 12697656 trascriptional regulation,stimulation inferred by curator,electrophoretic mobility shift assay TFlink
SMARCA4 MS4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MS4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MS4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MS4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MS4A2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
POU2F2 MS4A2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 MS4A2 18185580 25416803 mrna cleavage,inhibition array technology TarBase

Source Target Pmid Interactiontype Methods Database
PTPN6 MS4A2 14525934 25348397 9379041 N/A experimental interaction detection,in vitro ComPPI,HPRD
VAV1 MS4A2 25348397 N/A physical interaction ComPPI
SYK MS4A2 14525934 25348397 8071371 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
CBLB MS4A2 25348397 N/A physical interaction ComPPI
LYN MS4A2 14525934 19356729 25348397 7528770 7612892 N/A experimental interaction detection,in vivo ComPPI,HPRD
PTPN11 MS4A2 14525934 25348397 9379041 N/A experimental interaction detection,in vitro ComPPI,HPRD
PRKCD MS4A2 14525934 19356729 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
GRB2 MS4A2 14525934 25348397 8995445 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD
HSP90AA1 MS4A2 14525934 19356729 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MS4A2 AKT1 14525934 19356729 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MS4A2 FCER1A 14525934 1535625 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MS4A2 APP 25348397 N/A physical interaction ComPPI
MS4A2 TMEM86A 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
LYN MS4A2 19356729 22845063 27898060 7528770 7612892 stimulant N/A OmniPath
MS4A2 LYN 19356729 22845063 27898060 7528770 7612892 N/A N/A OmniPath
CAMK1 MS4A2 15339926 27898060 N/A N/A OmniPath

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