Gene Information gene info

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GENE：RASGRP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RASGRP2
FullNmae RAS guanyl releasing protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9879
EnsembleID ENSG00000068831
Uniprot Q7LDG7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RASGRP2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
RASGRP2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RASGRP2 GO:0001558,GO:0005085,GO:0005085,GO:0005085,GO:0005509,GO:0005509,GO:0005829,GO:0005829,GO:0005886,GO:0005886,GO:0007165,GO:0007265,GO:0007265,GO:0008289,GO:0019992,GO:0032587,GO:0043005,GO:0043547,GO:0043547,GO:0045202,GO:0071277

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RASGRP2 hsa:10235 path:hsa04010 MAPK signaling pathway - Homo sapiens (human)
RASGRP2 hsa:10235 path:hsa04014 Ras signaling pathway - Homo sapiens (human)
RASGRP2 hsa:10235 path:hsa04015 Rap1 signaling pathway - Homo sapiens (human)
RASGRP2 hsa:10235 path:hsa04062 Chemokine signaling pathway - Homo sapiens (human)
RASGRP2 hsa:10235 path:hsa04611 Platelet activation - Homo sapiens (human)
RASGRP2 hsa:10235 path:hsa05200 Pathways in cancer - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 RASGRP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RASGRP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RASGRP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RASGRP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RASGRP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 RASGRP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RASGRP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 RASGRP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
PRKACA RASGRP2 22135298 phosphorylation N/A PhosphoSite
RASGRP2 RAP1A 25361965 interaction type N/A PTMCode2
RAP1A RASGRP2 25361965 interaction type N/A PTMCode2
RASGRP2 HRAS 25361965 interaction type N/A PTMCode2
HRAS RASGRP2 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
KRAS RASGRP2 25348397 N/A in vitro,in vivo ComPPI
RAP1A RASGRP2 25348397 N/A in vitro,in vivo ComPPI
RASGRP2 DISP3 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
RASGRP2 NRAS 25348397 N/A in vitro,in vivo ComPPI
RASGRP2 APP 25348397 N/A physical interaction ComPPI
FAM118B RASGRP2 16169070 24234451 25348397 physical association two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct

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