Gene Information gene info

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GENE：DBR1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DBR1
FullNmae debranching RNA lariats 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15594
EnsembleID ENSG00000138231
Uniprot Q9UK59

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DBR1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
DBR1 cuproptosis 36010978 Derived from the genome-wide CRISPR-Cas9 loss-of-function test reported in previous literature, 347 potential cuproptosis-related genes (FDR < 0.05) were identified, and for a detailed list of genes, see聽Supplementary Table S1. Cuproptosis-related genes

Go Annotation:

GeneSymbol Go id
DBR1 GO:0000375,GO:0000398,GO:0003723,GO:0005634,GO:0005634,GO:0005654,GO:0008419,GO:0008419,GO:0046872

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DBR1 CREB1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB
LYL1 DBR1 18160048 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 DBR1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 DBR1 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 DBR1 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 DBR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DBR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 DBR1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000001EB3 DBR1 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001FC26E DBR1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 DBR1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000013ABA3 DBR1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000519450 DBR1 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003AA845 DBR1 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
BAG3 DBR1 25348397 N/A physical interaction ComPPI
TP53BP1 DBR1 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
NTRK1 DBR1 25348397 N/A physical interaction ComPPI
CLK1 DBR1 25348397 N/A physical interaction ComPPI
XPO1 DBR1 25348397 N/A physical interaction ComPPI
EGFR DBR1 24189400 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
MTREX DBR1 25348397 N/A physical interaction ComPPI
CAND1 DBR1 25348397 N/A physical interaction ComPPI
DHX38 DBR1 25348397 N/A physical interaction ComPPI
KCTD17 DBR1 25348397 N/A physical interaction ComPPI
CWF19L1 DBR1 25348397 N/A physical interaction ComPPI
CSNK1A1 DBR1 23455922 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
DBR1 MPLKIP 25348397 N/A physical interaction ComPPI
SPTAN1 DBR1 24234451 30021884 physical association cross-linking study IntAct

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