Gene Information gene info

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GENE：EDAR

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EDAR
FullNmae ectodysplasin A receptor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:2895
EnsembleID ENSG00000135960
Uniprot Q9UNE0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EDAR ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
EDAR GO:0001942,GO:0004888,GO:0004888,GO:0005515,GO:0005886,GO:0005886,GO:0006915,GO:0008544,GO:0010628,GO:0016020,GO:0030154,GO:0038023,GO:0042475,GO:0043123,GO:0043473,GO:0045177,GO:0046330,GO:0060662,GO:1901224

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
EDAR hsa:10913 path:hsa04060 Cytokine-cytokine receptor interaction - Homo sapiens (human)
EDAR hsa:10913 path:hsa04064 NF-kappa B signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 EDAR 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EDAR 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 EDAR 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 EDAR 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002AB575 EDAR 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000393C7 EDAR 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00006097A6 EDAR 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS00002367FA EDAR 22291592 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRAF3 EDAR 11035039 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
FADD EDAR 25348397 N/A physical interaction ComPPI
TRAF1 EDAR 11035039 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
TRAF2 EDAR 11035039 14525934 25348397 N/A experimental interaction detection,in vivo ComPPI,HPRD
MAP3K14 EDAR 11035039 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
EDA EDAR 11035039 11309369 14525934 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,IntAct
EDAR EDARADD 11780064 11882293 14525934 17354266 20222921 24234451 25348397 27898060 physical association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
EDAR TRADD 25348397 N/A physical interaction ComPPI
EDA EDAR 11035039 11309369 12084975 18304980 27898060 stimulant N/A OmniPath

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