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GENE：POLR2D

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol POLR2D
FullNmae RNA polymerase II subunit D
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9191
EnsembleID ENSG00000144231
Uniprot O15514

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
POLR2D pyroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR2D immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
POLR2D ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
POLR2D GO:0000166,GO:0005515,GO:0005634,GO:0005654,GO:0005654,GO:0005665,GO:0005665,GO:0005829,GO:0006366,GO:0006366,GO:0006367,GO:0016607,GO:0031369,GO:0034402

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
POLR2D hsa:5433 path:hsa03020 RNA polymerase - Homo sapiens (human)
POLR2D hsa:5433 path:hsa03420 Nucleotide excision repair - Homo sapiens (human)
POLR2D hsa:5433 path:hsa05016 Huntington disease - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 POLR2D 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 POLR2D 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 POLR2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA POLR2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF POLR2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 POLR2D 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004505E4 POLR2D 20371350 21572407 23592263 25416803 26701625 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS00000A07C1 POLR2D 20371350 21572407 23592263 25416803 26701625 mrna cleavage,inhibition nucleotide sequence identification,clip TarBase
URS000021D7C8 POLR2D 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000015B295 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000016FD1B POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004DA9DB POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000017EA6A POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00003D8730 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000023133F POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000012930C POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000015188E POLR2D 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002CE0C6 POLR2D 21572407 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000324096 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000032EF64 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000031E12 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000000B1C9 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000029979D POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000237CBD POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000122ED0 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000052E1A6 POLR2D 21572407 23592263 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS0000214763 POLR2D 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F POLR2D 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004B4B85 POLR2D 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000065FDF POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000045DBD POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005606AA POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D2680 POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000753AD POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000EC1BE POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001481F9 POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075BDAA POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C POLR2D 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 POLR2D 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
POLR2D POLR2B 25361965 interaction type N/A PTMCode2
POLR2B POLR2D 25361965 interaction type N/A PTMCode2
POLR2D GTF2B 25361965 interaction type N/A PTMCode2
GTF2B POLR2D 25361965 interaction type N/A PTMCode2
POLR2D POLR2F 25361965 interaction type N/A PTMCode2
POLR2F POLR2D 25361965 interaction type N/A PTMCode2
POLR2E POLR2D 25361965 interaction type N/A PTMCode2
POLR2D POLR2E 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 POLR2D 25348397 N/A physical interaction ComPPI
FTL POLR2D 25348397 N/A physical interaction ComPPI
POLR2L POLR2D 10567706 14525934 21988832 24234451 25348397 physical association two hybrid,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
SNRPA1 POLR2D 25348397 N/A physical interaction ComPPI
MED21 POLR2D 25348397 N/A physical interaction ComPPI
SRC POLR2D 25348397 N/A physical interaction ComPPI
SMARCD1 POLR2D 25348397 N/A physical interaction ComPPI
RBBP6 POLR2D 18624398 24234451 25348397 physical association two hybrid ComPPI,IntAct
CPNE2 POLR2D 25348397 N/A physical interaction ComPPI
MED1 POLR2D 25348397 N/A physical interaction ComPPI
WWP2 POLR2D 25348397 N/A physical interaction ComPPI
XRCC5 POLR2D 25348397 N/A physical interaction ComPPI
PSMB9 POLR2D 25348397 N/A physical interaction ComPPI
TRIM29 POLR2D 25348397 N/A physical interaction ComPPI
CTR9 POLR2D 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LMO2 POLR2D 25348397 N/A physical interaction ComPPI
ACTR1A POLR2D 25348397 N/A physical interaction ComPPI
MED9 POLR2D 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
YWHAE POLR2D 25348397 N/A physical interaction ComPPI
GTF2F1 POLR2D 25348397 N/A physical interaction ComPPI
POLR2E POLR2D 10567706 14525934 24234451 25348397 27193682 physical association experimental interaction detection,physical interaction,electron tomography,in vitro ComPPI,HPRD,IntAct
POLR2A POLR2D 10567706 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
MED28 POLR2D 25348397 N/A physical interaction ComPPI
MED26 POLR2D 15175163 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT5H POLR2D 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
LIMK1 POLR2D 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ELP2 POLR2D 25348397 N/A physical interaction ComPPI
ELAVL1 POLR2D 25348397 N/A physical interaction ComPPI
ELOA POLR2D 25348397 N/A physical interaction ComPPI
ESR1 POLR2D 14525934 15604093 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
MCM3 POLR2D 25348397 N/A physical interaction ComPPI
RECQL5 POLR2D 25348397 N/A anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
BRCA1 POLR2D 25348397 N/A physical interaction ComPPI
MCFD2 POLR2D 25348397 N/A physical interaction ComPPI
POLR2K POLR2D 10567706 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SMARCD3 POLR2D 25348397 N/A physical interaction ComPPI
POLR2J POLR2D 25348397 N/A physical interaction ComPPI
DCTN2 POLR2D 25348397 N/A physical interaction ComPPI
RNGTT POLR2D 25348397 N/A physical interaction ComPPI
POLR2C POLR2D 10567706 14525934 18562274 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
POLR2G POLR2D 14525934 24234451 25348397 26496610 9528765 association anti tag coimmunoprecipitation,two hybrid,experimental interaction detection,physical interaction,in vitro,in vivo,two hybrid ComPPI,HPRD,IntAct
NR5A2 POLR2D 14525934 15604093 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
MED19 POLR2D 15175163 21729782 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2D POLR2H 10567706 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
POLR2D POLR2B 10567706 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
POLR2D MED10 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2D MED29 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
POLR2D RPAP2 25348397 N/A physical interaction ComPPI
POLR2D EMX1 25348397 N/A physical interaction ComPPI
POLR2D IKBKG 25348397 N/A physical interaction ComPPI
POLR2D ZSCAN1 25348397 N/A physical interaction ComPPI
POLR2D INTS3 25348397 N/A physical interaction ComPPI
POLR2D INTS5 25348397 N/A physical interaction ComPPI
POLR2D INTS6 25348397 N/A physical interaction ComPPI
POLR2D INTS10 25348397 N/A physical interaction ComPPI
POLR2D POLR2I 25348397 N/A physical interaction ComPPI
POLR2D GPN3 25348397 N/A physical interaction ComPPI
POLR2D PIH1D1 25348397 N/A physical interaction ComPPI
POLR2D RPRD1B 25348397 N/A physical interaction ComPPI
POLR2D MYZAP 25348397 N/A physical interaction ComPPI
POLR2D POLR2M 25348397 N/A physical interaction ComPPI
POLR2D PUS7 25348397 N/A physical interaction ComPPI
POLR2D RPRD1A 25348397 N/A physical interaction ComPPI
POLR2D SYDE1 25348397 N/A physical interaction ComPPI
POLR2D ASB6 25348397 N/A physical interaction ComPPI
POLR2D CCN6 25348397 N/A physical interaction ComPPI
POLR2D ERCC2 24234451 25348397 27193682 physical association electron tomography ComPPI,IntAct
HOXC9 POLR2D 25348397 N/A physical interaction ComPPI
POLR2D ATF7IP 10777215 14525934 N/A experimental interaction detection HPRD
POLR2D POLR2D 10567706 14525934 N/A experimental interaction detection HPRD
NUDCD1 POLR2D 24234451 29021621 association anti tag coimmunoprecipitation IntAct

Visualization










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