Gene Information gene info

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GENE：MX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MX2
FullNmae MX dynamin like GTPase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:7533
EnsembleID ENSG00000183486
Uniprot P20592

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MX2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MX2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MX2 GO:0003924,GO:0005515,GO:0005525,GO:0005634,GO:0005643,GO:0005737,GO:0005829,GO:0005874,GO:0006952,GO:0008017,GO:0009615,GO:0015031,GO:0016020,GO:0035455,GO:0045087,GO:0046822,GO:0051028,GO:0051607,GO:0051607,GO:0051726

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
MX2 hsa:4600 path:hsa03250 Viral life cycle - HIV-1 - Homo sapiens (human)
MX2 hsa:4600 path:hsa05160 Hepatitis C - Homo sapiens (human)
MX2 hsa:4600 path:hsa05162 Measles - Homo sapiens (human)
MX2 hsa:4600 path:hsa05164 Influenza A - Homo sapiens (human)
MX2 hsa:4600 path:hsa05165 Human papillomavirus infection - Homo sapiens (human)
MX2 hsa:4600 path:hsa05171 Coronavirus disease - COVID-19 - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 MX2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
PRDM14 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TAL1 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 MX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001EFBE3 MX2 18057241 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B7E30 MX2 19536157 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00003BBF48 MX2 19536157 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002AB575 MX2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F MX2 19536157 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00004AE8D3 MX2 25416803 27418678 mrna cleavage,inhibition clip TarBase
URS00001CF056 MX2 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIAS2 MX2 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EHMT2 MX2 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CFTR MX2 25348397 N/A physical interaction ComPPI
MX2 ATRIP 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct

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