Gene Information gene info

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GENE：MED22

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol MED22
FullNmae mediator complex subunit 22
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11477
EnsembleID ENSG00000148297
Uniprot Q15528

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
MED22 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
MED22 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
MED22 GO:0003712,GO:0005515,GO:0005634,GO:0005737,GO:0016592,GO:0016592,GO:0032968,GO:0051123,GO:0060261,GO:0070847

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
SMARCA4 MED22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF MED22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 MED22 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ETS1 MED22 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 MED22 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 MED22 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000003ABC4 MED22 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000048BA36 MED22 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001597DC MED22 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001C770D MED22 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
TP53BP1 MED22 24234451 25348397 29656893 association proximity-dependent biotin identification ComPPI,IntAct
MED21 MED22 25348397 N/A physical interaction ComPPI
MED8 MED22 12584197 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
FBXW7 MED22 25348397 N/A physical interaction ComPPI
MED1 MED22 25348397 N/A physical interaction ComPPI
MED24 MED22 25348397 N/A physical interaction ComPPI
SOX2 MED22 25348397 N/A physical interaction ComPPI
MED22 MED30 12584197 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
MED22 MED9 14525934 14638676 15175163 24234451 25348397 association anti tag coimmunoprecipitation,experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,IntAct
MED22 MED10 12584197 14576168 14638676 15175163 24234451 24882805 25348397 association,physical association anti tag coimmunoprecipitation,electron microscopy,physical interaction,ion exchange chromatography ComPPI,IntAct
MED22 MED19 14576168 14638676 15175163 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED22 MED12 25348397 N/A physical interaction ComPPI
MED22 CDK8 23602568 24234451 25348397 29568061 association pull down,physical interaction,tandem affinity purification,proximity-dependent biotin identification ComPPI,IntAct
MED22 MED4 25348397 N/A physical interaction ComPPI
MED22 EPAS1 25348397 N/A physical interaction ComPPI
MED22 CDK19 15175163 23602568 24234451 25348397 association,physical association physical interaction,ion exchange chromatography,tandem affinity purification ComPPI,IntAct
MED22 CCNC 25348397 N/A physical interaction ComPPI
MED22 TCL1B 25348397 N/A physical interaction ComPPI
MED22 MED20 25348397 N/A physical interaction ComPPI
MED22 MED23 25348397 N/A physical interaction ComPPI
MED22 BIRC5 25348397 N/A physical interaction ComPPI
MED22 KSR1 24234451 25348397 27086506 association anti tag coimmunoprecipitation ComPPI,IntAct
MED28 MED22 24234451 24882805 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MED18 MED22 24234451 24882805 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAN MED22 25348397 N/A anti tag coimmunoprecipitation ComPPI
MED22 TSH 25348397 N/A anti tag coimmunoprecipitation ComPPI

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