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GENE：ARIH2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ARIH2
FullNmae ariadne RBR E3 ubiquitin protein ligase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:690
EnsembleID ENSG00000177479
Uniprot O95376

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ARIH2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ARIH2 GO:0000151,GO:0000209,GO:0000209,GO:0004842,GO:0005515,GO:0005634,GO:0005654,GO:0005737,GO:0005737,GO:0006511,GO:0006511,GO:0008270,GO:0016567,GO:0031624,GO:0031624,GO:0032436,GO:0048588,GO:0061630,GO:0070534,GO:0070936,GO:0071425,GO:1903955

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR ARIH2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ARIH2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ARIH2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ARIH2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000170CF4 ARIH2 20018759 rna interference,inhibition array technology,experimental interaction detection miRSponge
URS0000170CF4 ARIH2 20018759 25416803 mrna cleavage,inhibition array technology,experimental interaction detection TarBase
URS000006FDD4 ARIH2 19296935 25416803 mrna cleavage,inhibition quantitative reverse transcription pcr TarBase
URS00000DDD35 ARIH2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS00000FC8EB ARIH2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000148B91 ARIH2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000753AD ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000AD002 ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002198F3 ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000027352D ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000366551 ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000041FA2C ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00004F2EB0 ARIH2 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 ARIH2 20371350 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
UBE2L3 ARIH2 25361965 interaction type N/A PTMCode2
ARIH2 UBE2L3 25361965 interaction type N/A PTMCode2
GFI1 ARIH2 25361965 interaction type N/A PTMCode2
ARIH2 GFI1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
CUL5 ARIH2 24076655 24234451 25348397 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARIH2 KAT5 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 DLST 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 EEF1A1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 PTN 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 BUB1 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 UBE2L3 10431818 11722579 14525934 15545318 16118314 16169070 19340006 19549727 22037423 24076655 24234451 25224329 25348397 27898060 association,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct,OmniPath
ARIH2 SCAMP2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 UTP14A 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 UGP2 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
ARIH2 ARAP1 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 EEF1G 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 RPL8 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 CEP126 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
ARIH2 IL4R 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 KCNQ2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 SGCE 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 SLC1A6 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 EML4 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 WDR91 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 ENSA 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 PPP2R1A 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 TP53 14525934 16169070 22819825 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
ARIH2 EEF1A1P5 25348397 N/A physical interaction ComPPI
ARIH2 GFI1 25348397 N/A physical interaction ComPPI
ARIH2 UBE2L6 19549727 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARIH2 UBE2E2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2T 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2D1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2D2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2D3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2D4 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2E1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2E3 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2V1 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 UBE2R2 19549727 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 DISC1 17043677 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARIH2 PML 25348397 N/A physical interaction ComPPI
ARIH2 UBE2N 25348397 N/A physical interaction ComPPI
ARIH2 UBC 25348397 N/A physical interaction ComPPI
ARIH2 MDM2 22819825 22940738 24234451 25348397 27898060 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct,OmniPath
ARIH2 NOTCH1 23022380 24234451 25348397 association physical interaction,tandem affinity purification ComPPI,IntAct
ARIH2 VCP 25348397 N/A physical interaction ComPPI
ARIH2 TRIM27 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 PHF7 22493164 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 RHEB 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
ARIH2 NEDD8 25348397 N/A physical interaction ComPPI
ARIH2 APEX1 25348397 N/A physical interaction ComPPI
ARIH2 EHD1 25348397 N/A physical interaction ComPPI
ARIH2 PAPSS2 25348397 N/A physical interaction ComPPI
ARIH2 PDLIM1 25348397 N/A physical interaction ComPPI
ARIH2 HK2 25348397 N/A physical interaction ComPPI
ARIH2 NUBP1 25348397 N/A physical interaction ComPPI
ARIH2 TWF2 25348397 N/A physical interaction ComPPI
ARIH2 PABPN1 25348397 N/A physical interaction ComPPI
ARIH2 REL 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
ARIH2 CCDC33 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
ARIH2 ELOB 24076655 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARIH2 ELOC 24076655 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ARIH2 SOCS6 25348397 N/A physical interaction ComPPI
ARIH2 RAB40A 25348397 N/A physical interaction ComPPI
ARIH2 ASB9 25348397 N/A physical interaction ComPPI
ARIH2 ZFP41 25348397 N/A physical interaction ComPPI
ARIH2 NTRK1 25348397 N/A physical interaction ComPPI
ARIH2 BMX 25348397 N/A physical interaction ComPPI
ARIH2 TULP3 25348397 N/A physical interaction ComPPI
ARIH2 WSB2 25348397 N/A physical interaction ComPPI
ARIH2 PYCARD 25348397 N/A physical interaction ComPPI
ARIH2 NLRP3 25348397 N/A physical interaction ComPPI
ARIH2 KEAP1 25348397 N/A physical interaction ComPPI
ARIH2 PAX6 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ARIH2 CRX 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CBR3 ARIH2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct

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