GENE：CLCN7
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | CLCN7 |
| FullNmae | chloride voltage-gated channel 7 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:2025 |
| EnsembleID | ENSG00000103249 |
| Uniprot | P51798 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| CLCN7 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
| CLCN7 | apoptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| CLCN7 | GO:0005247,GO:0005254,GO:0005515,GO:0005524,GO:0005765,GO:0005765,GO:0005765,GO:0015108,GO:0015297,GO:0016020,GO:0030321,GO:0034707,GO:0043231,GO:1902476 |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | CLCN7 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| GATA2 | CLCN7 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CTCF | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| MITF | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| VDR | CLCN7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00004E008F | CLCN7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS00001F0C23 | CLCN7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
| URS000033B548 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000116F83 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004929F1 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002373FD | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000077DDE | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000C403E | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000585553 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00000BE495 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS0000355E82 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00003FBC84 | CLCN7 | 23592263 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000007F792 | CLCN7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00002004E0 | CLCN7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS00004900F1 | CLCN7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| URS000076B539 | CLCN7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| LMNA | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| CD44 | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| VAPA | CLCN7 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| ATP6AP2 | CLCN7 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| VAPB | CLCN7 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| TENT5A | CLCN7 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| UBE2A | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| LGALS8 | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| CREB3 | CLCN7 | 21516116 24234451 25348397 | physical association | two hybrid,physical interaction | ComPPI,IntAct |
| RAB9A | CLCN7 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| TRIM25 | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| BIRC7 | CLCN7 | 25348397 | N/A | physical interaction | ComPPI |
| TGOLN2 | CLCN7 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| XRCC3 | CLCN7 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| BET1 | CLCN7 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
| RAB5C | CLCN7 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CD53 | CLCN7 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| GDAP1 | CLCN7 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
| GOLT1B | CLCN7 | 24234451 25348397 26496610 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
| CLCN7 | PACS1 | 14525934 15692563 | N/A | experimental interaction detection | HPRD |
| OSTM1 | CLCN7 | 14525934 16525474 27898060 | N/A | experimental interaction detection | HPRD,OmniPath |