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GENE：ENPP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ENPP4
FullNmae ectonucleotide pyrophosphatase/phosphodiesterase 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:3359
EnsembleID ENSG00000001561
Uniprot Q9Y6X5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ENPP4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ENPP4 GO:0005515,GO:0005886,GO:0007596,GO:0016020,GO:0030194,GO:0046130,GO:0046872,GO:0047710,GO:0070062,GO:0101003

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ENPP4 hsa:22875 path:hsa00230 Purine metabolism - Homo sapiens (human)
ENPP4 hsa:22875 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ENPP4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 ENPP4 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ENPP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ENPP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ENPP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00000F31F4 ENPP4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS00000B59A2 ENPP4 19074876 25416803 mrna cleavage,inhibition array technology TarBase
URS000006FDD4 ENPP4 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000065D58 ENPP4 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F ENPP4 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 ENPP4 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000315338 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C11BC ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C0FCB ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 ENPP4 21572407 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000058BB84 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000031602A ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000251D0B ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075ADAC ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075D1FC ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000018CD09 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000030F801 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000195F5B ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000016914 ENPP4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000166778 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000043D2C1 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004BC299 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000EE7F0 ENPP4 21572407 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
LGALS3 ENPP4 25348397 N/A physical interaction ComPPI
SOX2 ENPP4 25348397 N/A physical interaction ComPPI
LGALS8 ENPP4 25348397 N/A physical interaction ComPPI
LPAR1 ENPP4 25348397 N/A physical interaction ComPPI
LGALS9 ENPP4 25348397 N/A physical interaction ComPPI
IL17RC ENPP4 25348397 N/A physical interaction ComPPI

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