Gene Information gene info

GENE:HEMK1

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HEMK1
FullNmae HemK methyltransferase family member 1
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24923
EnsembleID ENSG00000114735
Uniprot Q9Y5R4

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HEMK1 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HEMK1 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HEMK1 GO:0003677,GO:0005515,GO:0005739,GO:0006306,GO:0008170,GO:0008276,GO:0008757,GO:0019538,GO:0102559

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 HEMK1 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 HEMK1 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HEMK1 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002E728C HEMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F HEMK1 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS000017EA6A HEMK1 22012620 22291592 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 HEMK1 22012620 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PEF1 HEMK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PSMB4 HEMK1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEMK1 CHN1 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HEMK1 CDC23 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
HEMK1 NDUFS7 25348397 N/A physical interaction ComPPI
HEMK1 TRMT1 25348397 N/A physical interaction ComPPI
HEMK1 MAGED1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEMK1 POU2AF1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEMK1 INCA1 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEMK1 UBQLN2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEMK1 TUBGCP5 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HEMK1 AKAP8L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct

Visualization