GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
HEMK1 |
FullNmae |
HemK methyltransferase family member 1 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:24923 |
EnsembleID |
ENSG00000114735 |
Uniprot |
Q9Y5R4 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
HEMK1 |
immunogenic |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
HEMK1 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
HEMK1 |
GO:0003677,GO:0005515,GO:0005739,GO:0006306,GO:0008170,GO:0008276,GO:0008757,GO:0019538,GO:0102559 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
ETS1 |
HEMK1 |
18971253
20019798
|
trascriptional regulation,stimulation |
inferred by curator,chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
HEMK1 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
HEMK1 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS00002E728C |
HEMK1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00002E628F |
HEMK1 |
23592263
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000017EA6A |
HEMK1 |
22012620
22291592
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000021D7C8 |
HEMK1 |
22012620
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
PEF1 |
HEMK1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
PSMB4 |
HEMK1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
HEMK1 |
CHN1 |
24234451
25348397
25416956
|
physical association |
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
HEMK1 |
CDC23 |
24234451
25348397
25416956
|
physical association |
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid |
ComPPI,IntAct |
HEMK1 |
NDUFS7 |
25348397
|
N/A |
physical interaction |
ComPPI |
HEMK1 |
TRMT1 |
25348397
|
N/A |
physical interaction |
ComPPI |
HEMK1 |
MAGED1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
HEMK1 |
POU2AF1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
HEMK1 |
INCA1 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
HEMK1 |
UBQLN2 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
HEMK1 |
TUBGCP5 |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
HEMK1 |
AKAP8L |
24234451
25348397
|
physical association |
two hybrid,two hybrid array,two hybrid prey pooling approach |
ComPPI,IntAct |
Visualization