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GENE：HPS4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HPS4
FullNmae HPS4 biogenesis of lysosomal organelles complex 3 subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:15844
EnsembleID ENSG00000100099
Uniprot Q9NQG7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HPS4 mitotic_cd 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
HPS4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HPS4 GO:0005085,GO:0005085,GO:0005515,GO:0005737,GO:0005764,GO:0005765,GO:0005829,GO:0006605,GO:0006605,GO:0007040,GO:0007596,GO:0007599,GO:0016020,GO:0016192,GO:0030318,GO:0031085,GO:0031085,GO:0031267,GO:0031410,GO:0042470,GO:0042803,GO:0042827,GO:0046907,GO:0046983,GO:0048075,GO:0050821,GO:0060155,GO:1903232,GO:1903232,GO:1903232,GO:1903955

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR HPS4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 HPS4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 HPS4 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 HPS4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 HPS4 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 HPS4 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000079D48 HPS4 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001383CF HPS4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005ECFE5 HPS4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000037D7E5 HPS4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00003883FE HPS4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00001CC379 HPS4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 HPS4 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000076B539 HPS4 19536157 22927820 23313552 23824327 24906430 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000171525 HPS4 19536157 23313552 23824327 25416803 27418678 28735896 mrna cleavage,inhibition clip TarBase
URS0000013DD8 HPS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003CCBB9 HPS4 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000759FD9 HPS4 19536157 23824327 25416803 27418678 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RAC1 HPS4 20936779 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct

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