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GENE：HYI

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol HYI
FullNmae hydroxypyruvate isomerase (putative)
LocusType gene with protein product
Status Approved
HGNC_id HGNC:26948
EnsembleID ENSG00000178922
Uniprot Q5T013

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
HYI ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
HYI GO:0003674,GO:0005515,GO:0005575,GO:0008150,GO:0008903,GO:0046487

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
HYI hsa:81888 path:hsa00630 Glyoxylate and dicarboxylate metabolism - Homo sapiens (human)
HYI hsa:81888 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
GATA2 HYI 18971253 19941826 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 HYI 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
E2F1 HYI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 HYI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 HYI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS HYI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A HYI 18971253 trascriptional regulation,stimulation inferred by curator TFlink
VDR HYI 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
MAPRE1 HYI 25348397 N/A physical interaction ComPPI
CTBP1 HYI 25348397 N/A physical interaction ComPPI
HSPA9 HYI 25348397 N/A physical interaction ComPPI
SRSF11 HYI 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
TEX11 HYI 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SHBG HYI 25348397 N/A physical interaction ComPPI
ACY1 HYI 25348397 N/A physical interaction ComPPI

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