Gene Information gene info

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GENE：KLHL20

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol KLHL20
FullNmae kelch like family member 20
LocusType gene with protein product
Status Approved
HGNC_id HGNC:25056
EnsembleID ENSG00000076321
Uniprot Q9Y2M5

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
KLHL20 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
KLHL20 GO:0003779,GO:0004842,GO:0005515,GO:0005737,GO:0005794,GO:0005802,GO:0005802,GO:0005829,GO:0005829,GO:0006895,GO:0006895,GO:0007010,GO:0015031,GO:0015629,GO:0016567,GO:0016605,GO:0016605,GO:0019964,GO:0019964,GO:0030424,GO:0030425,GO:0031463,GO:0035455,GO:0043066,GO:0043161,GO:0043161,GO:0048471,GO:1990390,GO:1990390

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 KLHL20 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 KLHL20 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 KLHL20 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF KLHL20 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003E1A9 KLHL20 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000008DA94 KLHL20 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000012A1DD KLHL20 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS0000171525 KLHL20 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 KLHL20 20005803 rna interference,inhibition experimental interaction detection miRSponge
URS000055BBE5 KLHL20 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000008DA94 KLHL20 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000171525 KLHL20 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000003E1A9 KLHL20 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS000012A1DD KLHL20 20005803 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS00002075FA KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000006FDD4 KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 KLHL20 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS000023133F KLHL20 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 KLHL20 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F KLHL20 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS0000086A4D KLHL20 22100165 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
PIN1 KLHL20 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RARA KLHL20 25348397 N/A anti tag coimmunoprecipitation ComPPI
TMA16 KLHL20 25348397 N/A physical interaction ComPPI
CRK KLHL20 25348397 N/A physical interaction ComPPI
CPNE1 KLHL20 25348397 N/A physical interaction ComPPI
RHOA KLHL20 25348397 N/A physical interaction ComPPI
ARHGEF12 KLHL20 25348397 N/A physical interaction ComPPI
CUL3 KLHL20 20389280 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PIR KLHL20 25348397 N/A physical interaction ComPPI
NRGN KLHL20 25348397 N/A physical interaction ComPPI
ECT2 KLHL20 14525934 14668487 17395875 25348397 27898060 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD,OmniPath
XPO1 KLHL20 25348397 N/A physical interaction ComPPI
SUV39H1 KLHL20 23455924 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
TCEA1 KLHL20 25348397 N/A physical interaction ComPPI
PRIM1 KLHL20 25348397 N/A physical interaction ComPPI
COPS6 KLHL20 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRMP1 KLHL20 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
HIF1AN KLHL20 25348397 N/A physical interaction ComPPI
NUFIP2 KLHL20 25348397 N/A physical interaction ComPPI
ID2 KLHL20 25348397 N/A physical interaction ComPPI
EIF2S2 KLHL20 25348397 N/A physical interaction ComPPI
MTNR1A KLHL20 24234451 25348397 26514267 physical association two hybrid,physical interaction ComPPI,IntAct
RIF1 KLHL20 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
PML KLHL20 20389280 21840486 24234451 25348397 colocalization,physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,pull down,physical interaction,competition binding,fluorescence microscopy,confocal microscopy ComPPI,IntAct
CKAP5 KLHL20 25348397 N/A physical interaction ComPPI
EPAS1 KLHL20 21888897 25348397 27898060 N/A physical interaction ComPPI,OmniPath
UBE2M KLHL20 25348397 N/A physical interaction ComPPI
MAP3K13 KLHL20 25348397 N/A physical interaction ComPPI
TRIM33 KLHL20 25348397 N/A physical interaction ComPPI
ATXN2L KLHL20 25348397 N/A physical interaction ComPPI
LUC7L2 KLHL20 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
IVNS1ABP KLHL20 25348397 N/A physical interaction ComPPI
HELZ KLHL20 25348397 N/A physical interaction ComPPI
KLHL20 ACTA1 14525934 14668487 25348397 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD
KLHL20 GBP2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLHL20 ERG28 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
KLHL20 DAPK1 20389280 24234451 25348397 physical association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,two hybrid,physical interaction,competition binding ComPPI,IntAct
KLHL20 PRMT6 23455924 24234451 25348397 physical association anti tag coimmunoprecipitation,two hybrid,physical interaction ComPPI,IntAct
KLHL20 CORO7 25348397 N/A physical interaction ComPPI
KLHL20 SATB2 25348397 N/A physical interaction ComPPI
KLHL20 PRIM2 25348397 N/A physical interaction ComPPI
KLHL20 POLDIP3 25348397 N/A physical interaction ComPPI
KLHL20 ADSL 25348397 N/A physical interaction ComPPI
KLHL20 CNOT10 25348397 N/A physical interaction ComPPI
KLHL20 KLHL26 25348397 N/A physical interaction ComPPI
KLHL20 OSBPL11 25348397 N/A physical interaction ComPPI
KLHL20 CDKL5 25348397 N/A physical interaction ComPPI
KLHL20 KLHL22 25348397 N/A physical interaction ComPPI
KLHL20 RELB 25348397 N/A physical interaction ComPPI
KLHL20 RPRD1B 25348397 N/A physical interaction ComPPI
KLHL20 HOOK3 25348397 N/A physical interaction ComPPI
KLHL20 MITF 25348397 N/A physical interaction ComPPI

Visualization










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