GeneInfo:
| GeneAttribute |
GeneDescription |
| GeneSymbol |
KLHL5 |
| FullNmae |
kelch like family member 5 |
| LocusType |
gene with protein product |
| Status |
Approved |
| HGNC_id |
HGNC:6356 |
| EnsembleID |
ENSG00000109790 |
| Uniprot |
Q96PQ7 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
| KLHL5 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
| GeneSymbol |
Go id |
| KLHL5 |
GO:0003674,GO:0003779,GO:0005515,GO:0005737,GO:0005829,GO:0005856,GO:0008150 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| AR |
KLHL5 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| GATA2 |
KLHL5 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| YBX1 |
KLHL5 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
| FOXP3 |
KLHL5 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
| SMARCA4 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CEBPA |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| CTCF |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| E2F1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| EGR1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXA1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOXP1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| FOS |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| HNF4A |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| MITF |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| URS0000338542 |
KLHL5 |
20584899
|
rna interference,inhibition |
experimental interaction detection |
miRSponge |
| URS0000237AF9 |
KLHL5 |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
| URS0000338542 |
KLHL5 |
20584899
25416803
|
mrna cleavage,inhibition |
experimental interaction detection,experimental interaction detection |
TarBase |
| URS00000EC1BE |
KLHL5 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000000EF0B |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00000D0BB4 |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS000045B99E |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000016914 |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS0000170D8B |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| URS00003FA24D |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
| Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
| TK1 |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| GABARAPL2 |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| MAP1LC3B |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| SMN1 |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| CUL3 |
KLHL5 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
| MYC |
KLHL5 |
20195357
24234451
25348397
|
physical association |
display technology |
ComPPI,IntAct |
| MTNR1A |
KLHL5 |
25348397
|
N/A |
physical interaction |
ComPPI |
| FUS |
KLHL5 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization