GeneInfo:
GeneAttribute |
GeneDescription |
GeneSymbol |
KLHL5 |
FullNmae |
kelch like family member 5 |
LocusType |
gene with protein product |
Status |
Approved |
HGNC_id |
HGNC:6356 |
EnsembleID |
ENSG00000109790 |
Uniprot |
Q96PQ7 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol |
CellDeathType |
PMID |
Description |
GeneType |
KLHL5 |
ferroptosis |
38538696 |
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) |
retulator signature |
Go Annotation:
GeneSymbol |
Go id |
KLHL5 |
GO:0003674,GO:0003779,GO:0005515,GO:0005737,GO:0005829,GO:0005856,GO:0008150 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
AR |
KLHL5 |
20610535
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
GATA2 |
KLHL5 |
19941826
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
YBX1 |
KLHL5 |
19151767
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation assay |
TFlink |
FOXP3 |
KLHL5 |
20554955
|
trascriptional regulation,stimulation |
chromatin immunoprecipitation array |
TFlink |
SMARCA4 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CEBPA |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
CTCF |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
E2F1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
EGR1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXA1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOXP1 |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
FOS |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
HNF4A |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
MITF |
KLHL5 |
18971253
|
trascriptional regulation,stimulation |
inferred by curator |
TFlink |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
URS0000338542 |
KLHL5 |
20584899
|
rna interference,inhibition |
experimental interaction detection |
miRSponge |
URS0000237AF9 |
KLHL5 |
18185580
25416803
|
mrna cleavage,inhibition |
array technology |
TarBase |
URS0000338542 |
KLHL5 |
20584899
25416803
|
mrna cleavage,inhibition |
experimental interaction detection,experimental interaction detection |
TarBase |
URS00000EC1BE |
KLHL5 |
23824327
25416803
27418678
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000000EF0B |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00000D0BB4 |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS000045B99E |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000016914 |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS0000170D8B |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
URS00003FA24D |
KLHL5 |
19536157
25416803
|
mrna cleavage,inhibition |
clip |
TarBase |
Source |
Target |
Pmid |
Interactiontype |
Methods |
Database |
TK1 |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
GABARAPL2 |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
MAP1LC3B |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
SMN1 |
KLHL5 |
21900206
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
CUL3 |
KLHL5 |
21988832
24234451
25348397
|
physical association |
two hybrid,physical interaction |
ComPPI,IntAct |
MYC |
KLHL5 |
20195357
24234451
25348397
|
physical association |
display technology |
ComPPI,IntAct |
MTNR1A |
KLHL5 |
25348397
|
N/A |
physical interaction |
ComPPI |
FUS |
KLHL5 |
25348397
|
N/A |
physical interaction |
ComPPI |
Visualization