Gene Information gene info

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GENE：ORAI2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ORAI2
FullNmae ORAI calcium release-activated calcium modulator 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:21667
EnsembleID ENSG00000160991
Uniprot Q96SN7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ORAI2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ORAI2 GO:0002115,GO:0005515,GO:0015279,GO:0016020,GO:0030426,GO:0070588

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ORAI2 hsa:80228 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ORAI2 ORAI2 24243840 29145629 physical association inferred by curator Reactome

Source Target Pmid Interactiontype Methods Database
AR ORAI2 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 ORAI2 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 ORAI2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ORAI2 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
PRDM14 ORAI2 20953172 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TRIM28 ORAI2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00005651EE ORAI2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003CF1AD ORAI2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00004AC389 ORAI2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 ORAI2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000008A99 ORAI2 21572407 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000020CEC2 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000122F23 ORAI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000215483 ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002E728C ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00002B0B46 ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000076E54 ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000365675 ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00003E226A ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00000F4AC3 ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000017DBB8 ORAI2 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 ORAI2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003380CC ORAI2 23313552 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00005CC20C ORAI2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ORAI2 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001F373E ORAI2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000411752 ORAI2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000039A052 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000045147B ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004AAAFF ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C ORAI2 23313552 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001012BC ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001A7F58 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000B989F ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002FC5B0 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000C85B2 ORAI2 23824327 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000021202F ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003AD2AA ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000451A1 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075D2F5 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CCA62 ORAI2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000D0874 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000021D7C8 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000021D08 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000508C13 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000041E949 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000027080C ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000346991 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000070CD2 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000042E1F ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000039E1E1 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000239117 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000435A77 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000016FD1A ORAI2 23313552 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000047A67D ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002E0524 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000023BE29 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000BD1DE ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000078918 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000038446A ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000032835F ORAI2 23313552 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00004CFC54 ORAI2 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000512C88 ORAI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D ORAI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000259AE4 ORAI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B538 ORAI2 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000100748 ORAI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS000008B558 ORAI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000B0E50 ORAI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00005E1A16 ORAI2 25416803 26701625 mrna cleavage,inhibition clip TarBase
URS00000753AD ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EEF5F ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00004A9320 ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000F31F4 ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000048D44E ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000043C1C3 ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00001481F9 ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000005CE28 ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000CC005 ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075BDAA ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000EC1BE ORAI2 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
STIM1 ORAI2 25361965 interaction type N/A PTMCode2
ORAI2 STIM1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
SETDB1 ORAI2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
UNC119 ORAI2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
TRPC3 ORAI2 17360584 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CRACR2A ORAI2 20418871 24234451 25348397 physical association anti tag coimmunoprecipitation ComPPI,IntAct
COPS6 ORAI2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
GDF9 ORAI2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
MED31 ORAI2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
STIM1 ORAI2 19706554 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct

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