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GENE：PHKA2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PHKA2
FullNmae phosphorylase kinase regulatory subunit alpha 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:8926
EnsembleID ENSG00000044446
Uniprot P46019

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PHKA2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PHKA2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PHKA2 GO:0004689,GO:0005515,GO:0005516,GO:0005829,GO:0005886,GO:0005964,GO:0005975,GO:0005977,GO:0006091,GO:0036211

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PHKA2 hsa:5256 path:hsa04020 Calcium signaling pathway - Homo sapiens (human)
PHKA2 hsa:5256 path:hsa04910 Insulin signaling pathway - Homo sapiens (human)
PHKA2 hsa:5256 path:hsa04922 Glucagon signaling pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 PHKA2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 PHKA2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CTCF PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 PHKA2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000003ABC4 PHKA2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS00001C770D PHKA2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
UROD PHKA2 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
ITGAV PHKA2 25348397 N/A physical interaction ComPPI
SMAD9 PHKA2 15231748 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
BAG6 PHKA2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKA2 RAF1 25348397 N/A physical interaction ComPPI
PHKA2 UBE3A 25348397 N/A physical interaction ComPPI
PHKA2 ARRB2 17620599 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKA2 MMS19 25348397 N/A physical interaction ComPPI
PHKA2 CEP57 25348397 N/A physical interaction ComPPI
PHKA2 TP53 25348397 N/A physical interaction ComPPI
PHKA2 TUBGCP2 25348397 N/A physical interaction ComPPI
PHKA2 DOK4 25348397 N/A physical interaction ComPPI
PHKA2 GOLT1B 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PHKA2 AP5Z1 25348397 N/A physical interaction ComPPI
PHKA2 FOXK1 24234451 25348397 25609649 association physical interaction,tandem affinity purification ComPPI,IntAct
PHKA2 EYA2 25348397 N/A physical interaction ComPPI
STT3B PHKA2 24234451 30021884 physical association cross-linking study IntAct

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