Gene Information gene info

GENE:PNPLA4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol PNPLA4
FullNmae patatin like phospholipase domain containing 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:24887
EnsembleID ENSG00000006757
Uniprot P41247

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
PNPLA4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
PNPLA4 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
PNPLA4 GO:0004623,GO:0004806,GO:0004806,GO:0004806,GO:0005737,GO:0005739,GO:0005811,GO:0005829,GO:0008150,GO:0016020,GO:0016411,GO:0019433,GO:0019433,GO:0042572,GO:0047376,GO:0050253,GO:0051264,GO:0051265,GO:0055088

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
PNPLA4 hsa:8228 path:hsa00830 Retinol metabolism - Homo sapiens (human)
PNPLA4 hsa:8228 path:hsa01100 Metabolic pathways - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
PRDM14 PNPLA4 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
CEBPA PNPLA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF PNPLA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 PNPLA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 PNPLA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 PNPLA4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000338542 PNPLA4 18668040 25416803 mrna cleavage,inhibition experimental interaction detection TarBase
URS0000042E1F PNPLA4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000600E6 PNPLA4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000939AF PNPLA4 23824327 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000298BA3 PNPLA4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00000DDD35 PNPLA4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002B3783 PNPLA4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00002075FA PNPLA4 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS0000013DD8 PNPLA4 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP2B3 PNPLA4 25348397 N/A physical interaction ComPPI

Visualization