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GENE：RAB4A

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol RAB4A
FullNmae RAB4A, member RAS oncogene family
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9781
EnsembleID ENSG00000168118
Uniprot P20338

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
RAB4A ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
RAB4A GO:0003924,GO:0003924,GO:0003925,GO:0005515,GO:0005525,GO:0005525,GO:0015031,GO:0016192,GO:0019003,GO:0019882,GO:0030100,GO:0030659,GO:0031901,GO:0031982,GO:0032482,GO:0032593,GO:0048471,GO:0055038,GO:0070062,GO:0098837

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
RAB4A hsa:5867 path:hsa04144 Endocytosis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
CFTR RAB4A 16413502 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CD2AP RAB4A 20005715 interaction type N/A PSP

Source Target Pmid Interactiontype Methods Database
ESR1 RAB4A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 RAB4A 20019798 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA1 RAB4A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 RAB4A 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA3 RAB4A 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 RAB4A 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
FOXP3 RAB4A 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
SMARCA4 RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF RAB4A 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D RAB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000047E28E RAB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS000075AB14 RAB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00005586D0 RAB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 RAB4A 23446348 25416803 mrna cleavage,inhibition clip TarBase
URS0000308E4D RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000535FDD RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000049FAE8 RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000006F90B RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000010F787 RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001BCAC5 RAB4A 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000298BA3 RAB4A 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000355E82 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075C1E1 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002A8BC6 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000032AE90 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003E5ECC RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000075A760 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00002152A8 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000137EDE RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000019907A RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00001C770D RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000214763 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000047A8F RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS000006372A RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00000C5969 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS0000083D87 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase
URS00003FBC84 RAB4A 23313552 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CDK1 RAB4A 22135298 phosphorylation N/A PhosphoSite
CD2AP RAB4A 25361965 interaction type N/A PTMCode2
RAB4A CD2AP 25361965 interaction type N/A PTMCode2
STX4 RAB4A 25361965 interaction type N/A PTMCode2
RAB4A STX4 25361965 interaction type N/A PTMCode2
RABGEF1 RAB4A 25361965 interaction type N/A PTMCode2
RAB4A RABGEF1 25361965 interaction type N/A PTMCode2
RABEP1 RAB4A 25361965 interaction type N/A PTMCode2
RAB4A RABEP1 25361965 interaction type N/A PTMCode2
RAB4A GDI1 25361965 interaction type N/A PTMCode2
GDI1 RAB4A 25361965 interaction type N/A PTMCode2
RAB4A RUFY1 25361965 interaction type N/A PTMCode2
RUFY1 RAB4A 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
PIN1 RAB4A 10888662 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro ComPPI,HPRD,OmniPath
EXOC5 RAB4A 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
DYNLL1 RAB4A 11243854 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
RAB4A STX4 11063739 14525934 25348397 27898060 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
RAB4A GDI2 10512627 14525934 19570034 24234451 25348397 physical association anti tag coimmunoprecipitation,experimental interaction detection,fluorescent resonance energy transfer,physical interaction,in vitro ComPPI,HPRD,IntAct
RAB4A RABEP1 11788822 14525934 24234451 25348397 9524117 physical association two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
RAB4A KIF3B 12832475 14525934 25348397 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD
RAB4A CD2AP 12559036 14525934 25348397 N/A two hybrid,experimental interaction detection,physical interaction,in vitro,two hybrid ComPPI,HPRD
RAB4A RABAC1 10329441 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
RAB4A RAB11FIP1 25348397 N/A two hybrid,physical interaction,in vitro,in vivo ComPPI
RAB4A DYNC1LI1 11243854 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RAB4A RABGEF1 25348397 N/A in vitro,in vivo ComPPI
RAB4A RUFY1 11172003 14525934 25348397 N/A two hybrid,physical interaction,two hybrid ComPPI,HPRD
RAB4A RBSN 11788822 14525934 16034420 24234451 25348397 29997244 physical association bioluminescence resonance energy transfer,two hybrid,experimental interaction detection,physical interaction,two hybrid array,in vitro,in vivo,two hybrid prey pooling approach ComPPI,HPRD,IntAct
RAB4A PRKCI 12832475 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
RAB4A MAPK3 14525934 25348397 8112321 N/A experimental interaction detection,in vitro ComPPI,HPRD
RAB4A CHM 12535645 14525934 25348397 N/A two hybrid,two hybrid ComPPI,HPRD
RAB4A SOD2 123234 14525934 16169070 24234451 25348397 27898060 physical association experimental interaction detection,two hybrid pooling approach,two hybrid fragment pooling approach,in vitro,in vivo ComPPI,HPRD,IntAct,OmniPath
RAB4A ACTB 14525934 25348397 27898060 9013719 N/A experimental interaction detection,in vitro,in vivo ComPPI,HPRD,OmniPath
RAB4A TP53 14525934 16169070 24234451 25348397 physical association physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAB4A RAB5A 25348397 N/A physical interaction ComPPI
RAB4A RAB7A 25348397 N/A physical interaction ComPPI
RAB4A ZFYVE28 25348397 N/A physical interaction ComPPI
RAB4A HACE1 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAB4A KCNA5 25348397 N/A physical interaction ComPPI
RAB4A BAG3 25348397 N/A physical interaction ComPPI
RAB4A RABGAP1 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAB4A PTTG1IP 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAB4A IDH3A 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAB4A GRIPAP1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
RAB4A RABEP2 21988832 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
RAB4A ZNF830 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
RAB4A VPS52 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
RAB4A SCCPDH 25348397 N/A physical interaction ComPPI
RAB4A EREG 25348397 N/A physical interaction ComPPI
RAB4A GDI1 19570034 24234451 25348397 26496610 association,physical association anti tag coimmunoprecipitation,fluorescent resonance energy transfer,physical interaction ComPPI,IntAct
RAB4A LAMP1 25348397 N/A physical interaction ComPPI
RAB4A LRIG1 25348397 N/A physical interaction ComPPI
RAB4A RAB2B 25348397 N/A physical interaction ComPPI
RAB4A GRPR 25348397 N/A physical interaction ComPPI
RAB4A SLC22A9 25348397 N/A physical interaction ComPPI
RAB4A APBB3 14525934 16169070 24234451 25348397 physical association two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
RAB4A HGS 16962593 24234451 25348397 colocalization cosedimentation through density gradient ComPPI,IntAct
RAB4A PASK 21418524 24234451 25348397 phosphorylation reaction peptide array ComPPI,IntAct
RAB4A FAM71C 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CDK1 RAB4A 1425574 14525934 N/A experimental interaction detection HPRD
CFTR RAB4A 16413502 27898060 N/A N/A OmniPath
CHUK RAB4A 1425574 27898060 N/A N/A OmniPath
CDK1 RAB4A 1425574 24404161 27898060 N/A N/A OmniPath
NDRG1 RAB4A 17786215 27898060 stimulant N/A OmniPath

Visualization










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