GENE：RC3H2
GeneInfo:
| GeneAttribute | GeneDescription |
|---|---|
| GeneSymbol | RC3H2 |
| FullNmae | ring finger and CCCH-type domains 2 |
| LocusType | gene with protein product |
| Status | Approved |
| HGNC_id | HGNC:21461 |
| EnsembleID | ENSG00000056586 |
| Uniprot | Q9HBD1 |
Protein Structure:
Gene Description in Publicaton:
| GeneSymbol | CellDeathType | PMID | Description | GeneType |
|---|---|---|---|---|
| RC3H2 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
| GeneSymbol | Go id |
|---|---|
| RC3H2 | GO:0000209,GO:0000209,GO:0000209,GO:0000288,GO:0000932,GO:0001782,GO:0003677,GO:0003723,GO:0003725,GO:0003725,GO:0003729,GO:0006511,GO:0009791,GO:0009986,GO:0010494,GO:0016020,GO:0035264,GO:0035613,GO:0035613,GO:0042098,GO:0043029,GO:0043231,GO:0046872,GO:0048286,GO:0048535,GO:0048536,GO:0050852,GO:0060173,GO:0061470,GO:0061630,GO:0061630,GO:1901224,GO:2000320,GO:2000628 |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| ETS1 | RC3H2 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
| SMARCA4 | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| CEBPA | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| E2F4 | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| EGR1 | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOXA1 | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| FOS | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| ZNF263 | RC3H2 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| UBE2I | RC3H2 | 19549727 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| UBE2E2 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2E3 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2D2 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| UBC | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2N | RC3H2 | 19549727 24234451 25348397 26489670 27898060 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct,OmniPath |
| OGT | RC3H2 | 24234451 25348397 27705803 | association | tandem affinity purification | ComPPI,IntAct |
| UBE2K | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| TRIM25 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| ELAVL1 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2V1 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| UBE2V2 | RC3H2 | 25348397 | N/A | physical interaction | ComPPI |
| TIA1 | RC3H2 | 20412057 24234451 25348397 | colocalization | fluorescence microscopy | ComPPI,IntAct |
| TRIM8 | RC3H2 | 22493164 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
| RC3H2 | CYP19A1 | 25348397 | N/A | physical interaction | ComPPI |
| Source | Target | Pmid | Interactiontype | Methods | Database |
|---|---|---|---|---|---|
| URS00009BC987 | RC3H2 | 27087310 | direct interaction,inhibition | N/A | NPInter |