GENE:SCMH1
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SCMH1 |
FullNmae | Scm polycomb group protein homolog 1 |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:19003 |
EnsembleID | ENSG00000010803 |
Uniprot | Q96GD3 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SCMH1 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SCMH1 | GO:0003682,GO:0005515,GO:0005634,GO:0005654,GO:0031507,GO:0042393,GO:0045892,GO:0045892 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SCMH1 | hsa:22955 | path:hsa03083 | Polycomb repressive complex - Homo sapiens (human) |
Protein-Protein Interaction(String):
Gene-Drug Network:
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SCMH1 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
GATA1 | SCMH1 | 19941826 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
GATA2 | SCMH1 | 18971253 19941826 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
SMARCA4 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CEBPA | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOXA1 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
MITF | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
PRDM14 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
ZNF263 | SCMH1 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS00000F31F4 | SCMH1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00000B59A2 | SCMH1 | 19074876 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS00004B4B85 | SCMH1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00004AC389 | SCMH1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS000000B1C9 | SCMH1 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
TMEM11 | SCMH1 | 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
CDC42 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
GMNN | SCMH1 | 25348397 | N/A | in vitro | ComPPI |
MAGEA12 | SCMH1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
PCBD1 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
BMI1 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
PHC2 | SCMH1 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
PCGF2 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
HPCAL4 | SCMH1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
TOB1 | SCMH1 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
EWSR1 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
CBX4 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
RNF2 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
UBQLN4 | SCMH1 | 16713569 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid array | ComPPI,IntAct |
MAML3 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
UBQLN1 | SCMH1 | 24234451 25348397 25416956 | physical association | physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid | ComPPI,IntAct |
GNB2 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
PHC1 | SCMH1 | 10653359 25348397 27898060 | N/A | physical interaction,in vitro | ComPPI,OmniPath |
MOB4 | SCMH1 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
ZWINT | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | HK1 | 16169070 24234451 25348397 | physical association | two hybrid,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
SCMH1 | LYPLA2 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
SCMH1 | MYZAP | 25348397 | N/A | physical interaction,two hybrid fragment pooling approach | ComPPI |
SCMH1 | POLR2M | 16169070 24234451 25348397 | physical association | physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
SCMH1 | PHC3 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | MAGEA3 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | ACTBL2 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | ACTA2 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | PGK2 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | SFMBT1 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
SCMH1 | SFMBT2 | 24234451 25348397 | physical association | two hybrid,two hybrid array,two hybrid prey pooling approach | ComPPI,IntAct |
LZTR1 | SCMH1 | 25348397 | N/A | physical interaction | ComPPI |
SCMH1 | SCMH1 | 16169070 24234451 | physical association | two hybrid pooling approach | IntAct |