GENE:SMG7
GeneInfo:
GeneAttribute | GeneDescription |
---|---|
GeneSymbol | SMG7 |
FullNmae | SMG7 nonsense mediated mRNA decay factor |
LocusType | gene with protein product |
Status | Approved |
HGNC_id | HGNC:16792 |
EnsembleID | ENSG00000116698 |
Uniprot | Q92540 |
Protein Structure:
Gene Description in Publicaton:
GeneSymbol | CellDeathType | PMID | Description | GeneType |
---|---|---|---|---|
SMG7 | ferroptosis | 38538696 | The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) | retulator signature |
Go Annotation:
GeneSymbol | Go id |
---|---|
SMG7 | GO:0000184,GO:0000184,GO:0005515,GO:0005634,GO:0005697,GO:0005737,GO:0005829,GO:0005829,GO:0006406,GO:0035303,GO:0042162,GO:0042162,GO:0051721,GO:0070034 |
KEGG Annotation:
GeneSymbol | GeneID | Pathway | Pathway Name |
---|---|---|---|
SMG7 | hsa:9887 | path:hsa03015 | mRNA surveillance pathway - Homo sapiens (human) |
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
AR | SMG7 | 20610535 | trascriptional regulation,stimulation | chromatin immunoprecipitation array | TFlink |
ESR1 | SMG7 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
ETS1 | SMG7 | 18971253 20019798 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
GATA3 | SMG7 | 21878914 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
FOXA1 | SMG7 | 18971253 21878914 | trascriptional regulation,stimulation | inferred by curator,chromatin immunoprecipitation assay | TFlink |
YBX1 | SMG7 | 19151767 | trascriptional regulation,stimulation | chromatin immunoprecipitation assay | TFlink |
SMARCA4 | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
CTCF | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
E2F4 | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
EGR1 | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
FOS | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
GATA2 | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
HNF4A | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
SPI1 | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
TP53 | SMG7 | 18971253 | trascriptional regulation,stimulation | inferred by curator | TFlink |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
URS0000237AF9 | SMG7 | 18185580 25416803 | mrna cleavage,inhibition | array technology | TarBase |
URS000033EBB8 | SMG7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000600E6 | SMG7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00002367FA | SMG7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS00000DDD35 | SMG7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000324096 | SMG7 | 23622248 25416803 | mrna cleavage,inhibition | clash | TarBase |
URS0000077AED | SMG7 | 24374217 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS0000555DA6 | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00002CEB74 | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000004BACE | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000047944F | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00001CE046 | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS000006BE7D | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
URS00004CD810 | SMG7 | 23824327 25416803 | mrna cleavage,inhibition | clip | TarBase |
Source | Target | Pmid | Interactiontype | Methods | Database |
---|---|---|---|---|---|
RBM8A | SMG7 | 16452507 24234451 25348397 | association | anti bait coimmunoprecipitation,physical interaction | ComPPI,IntAct |
CDC16 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
BTRC | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
HNRNPL | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
XPO1 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
SMG1 | SMG7 | 16452507 24234451 25348397 | association | anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
MDM2 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
ODF2 | SMG7 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
FGFR3 | SMG7 | 16169070 24234451 25348397 | physical association | two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach | ComPPI,IntAct |
SMG6 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
SMG5 | SMG7 | 23348841 24234451 25348397 | association,physical association | pull down,in vivo | ComPPI,IntAct |
SSX2IP | SMG7 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
CENPJ | SMG7 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
UPF1 | SMG7 | 23348841 24234451 25348397 | association,physical association | anti tag coimmunoprecipitation,pull down,physical interaction | ComPPI,IntAct |
TRIM25 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
ELAVL1 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
TOMM20 | SMG7 | 24234451 25348397 29568061 | association | proximity-dependent biotin identification | ComPPI,IntAct |
FBXW11 | SMG7 | 25348397 | N/A | physical interaction | ComPPI |
CEP152 | SMG7 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
SMG7 | HBB | 25348397 | N/A | physical interaction | ComPPI |
SMG7 | PRMT6 | 25348397 | N/A | physical interaction | ComPPI |
SMG7 | PCM1 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
SMG7 | CEP44 | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
SMG7 | NINL | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
SMG7 | STIL | 24234451 25348397 26638075 | association | physical interaction,proximity-dependent biotin identification | ComPPI,IntAct |
SMG7 | SEC16A | 25348397 | N/A | physical interaction | ComPPI |
SMG7 | TP53 | 22653443 24234451 25348397 | association | anti tag coimmunoprecipitation,physical interaction | ComPPI,IntAct |
SMG7 | MTMR4 | 25348397 | N/A | physical interaction | ComPPI |
SMG7 | RIPK4 | 24234451 25348397 26972000 | association | anti tag coimmunoprecipitation | ComPPI,IntAct |