Gene Information gene info

GENE:SMG7

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SMG7
FullNmae SMG7 nonsense mediated mRNA decay factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:16792
EnsembleID ENSG00000116698
Uniprot Q92540

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SMG7 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SMG7 GO:0000184,GO:0000184,GO:0005515,GO:0005634,GO:0005697,GO:0005737,GO:0005829,GO:0005829,GO:0006406,GO:0035303,GO:0042162,GO:0042162,GO:0051721,GO:0070034

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SMG7 hsa:9887 path:hsa03015 mRNA surveillance pathway - Homo sapiens (human)

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR SMG7 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ESR1 SMG7 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
ETS1 SMG7 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA3 SMG7 21878914 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXA1 SMG7 18971253 21878914 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SMG7 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
SPI1 SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink
TP53 SMG7 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000237AF9 SMG7 18185580 25416803 mrna cleavage,inhibition array technology TarBase
URS000033EBB8 SMG7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000600E6 SMG7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00002367FA SMG7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000DDD35 SMG7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000324096 SMG7 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000077AED SMG7 24374217 25416803 mrna cleavage,inhibition clip TarBase
URS0000555DA6 SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00002CEB74 SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000004BACE SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000047944F SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001CE046 SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000006BE7D SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00004CD810 SMG7 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
RBM8A SMG7 16452507 24234451 25348397 association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
CDC16 SMG7 25348397 N/A physical interaction ComPPI
BTRC SMG7 25348397 N/A physical interaction ComPPI
HNRNPL SMG7 25348397 N/A physical interaction ComPPI
XPO1 SMG7 25348397 N/A physical interaction ComPPI
SMG1 SMG7 16452507 24234451 25348397 association anti bait coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MDM2 SMG7 25348397 N/A physical interaction ComPPI
ODF2 SMG7 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
FGFR3 SMG7 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach ComPPI,IntAct
SMG6 SMG7 25348397 N/A physical interaction ComPPI
SMG5 SMG7 23348841 24234451 25348397 association,physical association pull down,in vivo ComPPI,IntAct
SSX2IP SMG7 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
CENPJ SMG7 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
UPF1 SMG7 23348841 24234451 25348397 association,physical association anti tag coimmunoprecipitation,pull down,physical interaction ComPPI,IntAct
TRIM25 SMG7 25348397 N/A physical interaction ComPPI
ELAVL1 SMG7 25348397 N/A physical interaction ComPPI
TOMM20 SMG7 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
FBXW11 SMG7 25348397 N/A physical interaction ComPPI
CEP152 SMG7 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SMG7 HBB 25348397 N/A physical interaction ComPPI
SMG7 PRMT6 25348397 N/A physical interaction ComPPI
SMG7 PCM1 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SMG7 CEP44 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SMG7 NINL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SMG7 STIL 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
SMG7 SEC16A 25348397 N/A physical interaction ComPPI
SMG7 TP53 22653443 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SMG7 MTMR4 25348397 N/A physical interaction ComPPI
SMG7 RIPK4 24234451 25348397 26972000 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization