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GENE：SUPT6H

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SUPT6H
FullNmae SPT6 homolog, histone chaperone and transcription elongation factor
LocusType gene with protein product
Status Approved
HGNC_id HGNC:11470
EnsembleID ENSG00000109111
Uniprot Q7KZ85

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SUPT6H ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SUPT6H GO:0001825,GO:0003677,GO:0003723,GO:0005515,GO:0005654,GO:0006368,GO:0006397,GO:0008023,GO:0008380,GO:0010793,GO:0031491,GO:0032968,GO:0034728,GO:0042393,GO:0042393,GO:0045191,GO:0050684,GO:0051028,GO:0051147,GO:0140673

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
BMI1 SUPT6H 23180781 24457600 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
CEBPA SUPT6H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SUPT6H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SUPT6H 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SUPT6H 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000013DD8 SUPT6H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00003D5391 SUPT6H 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000016D2D4 SUPT6H 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
CDK2 SUPT6H 22135298 phosphorylation N/A PhosphoSite

Source Target Pmid Interactiontype Methods Database
RNF40 SUPT6H 25348397 N/A physical interaction ComPPI
GMNN SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
CDKN1A SUPT6H 25348397 N/A physical interaction ComPPI
EMD SUPT6H 25348397 N/A physical interaction ComPPI
VCP SUPT6H 25348397 N/A physical interaction ComPPI
TMA16 SUPT6H 25348397 N/A physical interaction ComPPI
UXT SUPT6H 25348397 N/A physical interaction ComPPI
BMI1 SUPT6H 25348397 N/A physical interaction ComPPI
VBP1 SUPT6H 25348397 N/A physical interaction ComPPI
ERBB2 SUPT6H 16273093 24234451 25348397 N/A protein array,physical interaction ComPPI,IntAct
SKAP1 SUPT6H 25348397 N/A physical interaction ComPPI
SMAD2 SUPT6H 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
YWHAZ SUPT6H 15161933 24234451 25348397 physical association pull down ComPPI,IntAct
TUBG1 SUPT6H 25348397 N/A physical interaction ComPPI
GAB1 SUPT6H 24234451 24728074 25348397 N/A fluorescence polarization spectroscopy ComPPI,IntAct
PPP1CA SUPT6H 25348397 N/A physical interaction ComPPI
CSNK2A1 SUPT6H 25348397 N/A physical interaction,protein kinase assay ComPPI
HNRNPL SUPT6H 25348397 N/A physical interaction ComPPI
NFATC2 SUPT6H 25348397 N/A physical interaction ComPPI
CTR9 SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
TMPO SUPT6H 25348397 N/A physical interaction ComPPI
LMO2 SUPT6H 25348397 N/A physical interaction ComPPI
EXOSC10 SUPT6H 25348397 N/A physical interaction ComPPI
CBX5 SUPT6H 19498464 24234451 25348397 association anti tag coimmunoprecipitation ComPPI,IntAct
POLR3E SUPT6H 25348397 N/A physical interaction ComPPI
TCEA1 SUPT6H 25348397 N/A physical interaction ComPPI
URI1 SUPT6H 25348397 N/A physical interaction ComPPI
POLR2E SUPT6H 25348397 N/A physical interaction ComPPI
POLR2A SUPT6H 25348397 N/A physical interaction ComPPI
STRAP SUPT6H 25348397 N/A physical interaction ComPPI
TUBGCP3 SUPT6H 25348397 N/A physical interaction ComPPI
MDC1 SUPT6H 25348397 N/A physical interaction ComPPI
EED SUPT6H 25348397 N/A physical interaction ComPPI
CUL7 SUPT6H 25348397 N/A physical interaction ComPPI
H3C1 SUPT6H 25348397 N/A physical interaction ComPPI
SUPT5H SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT4H1 SUPT6H 25348397 N/A physical interaction ComPPI
TRIM25 SUPT6H 25348397 N/A physical interaction ComPPI
SSRP1 SUPT6H 25348397 N/A physical interaction ComPPI
DDB2 SUPT6H 25348397 N/A physical interaction ComPPI
H2AX SUPT6H 25348397 N/A physical interaction ComPPI
ESR1 SUPT6H 25348397 N/A physical interaction ComPPI
ESR2 SUPT6H 24234451 25348397 25604459 association tandem affinity purification ComPPI,IntAct
BRCA1 SUPT6H 25348397 N/A physical interaction ComPPI
S100A10 SUPT6H 25348397 N/A physical interaction ComPPI
POLR1A SUPT6H 25348397 N/A physical interaction ComPPI
FBXW4 SUPT6H 25348397 N/A physical interaction ComPPI
DNAJB6 SUPT6H 23414517 24234451 25348397 physical association two hybrid fragment pooling approach ComPPI,IntAct
CEP250 SUPT6H 25348397 N/A physical interaction ComPPI
POLR2C SUPT6H 25348397 N/A anti tag coimmunoprecipitation,anti tag coimmunoprecipitation,physical interaction,physical interaction ComPPI
PFDN2 SUPT6H 25348397 N/A physical interaction ComPPI
EEF1D SUPT6H 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
CEP57 SUPT6H 25348397 N/A physical interaction ComPPI
CEP76 SUPT6H 25348397 N/A physical interaction ComPPI
PIH1D1 SUPT6H 25348397 N/A physical interaction ComPPI
RPRD1B SUPT6H 25348397 N/A physical interaction ComPPI
IWS1 SUPT6H 25348397 N/A physical interaction ComPPI
PDCD11 SUPT6H 25348397 N/A physical interaction ComPPI
WSB2 SUPT6H 25348397 N/A physical interaction ComPPI
SIRT7 SUPT6H 25348397 N/A physical interaction ComPPI
HAUS2 SUPT6H 25348397 N/A physical interaction ComPPI
SLC39A1 SUPT6H 25348397 N/A physical interaction ComPPI
PAAF1 SUPT6H 25348397 N/A physical interaction ComPPI
DEGS1 SUPT6H 25348397 N/A physical interaction ComPPI
FOS SUPT6H 20195357 24234451 25348397 physical association display technology ComPPI,IntAct
TP53 SUPT6H 25348397 N/A physical interaction ComPPI
MYZAP SUPT6H 25348397 N/A physical interaction ComPPI
POLR2M SUPT6H 25348397 N/A physical interaction ComPPI
RIOK3 SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
NCL SUPT6H 25348397 N/A physical interaction ComPPI
ANAPC7 SUPT6H 25348397 N/A physical interaction ComPPI
TMPO SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SGO1 SUPT6H 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
WDR48 SUPT6H 19615732 24234451 25348397 physical association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT6H OBSL1 25348397 N/A physical interaction ComPPI
SUPT6H PVRIG 25348397 N/A physical interaction ComPPI
SUPT6H TTC29 25348397 N/A physical interaction ComPPI
SUPT6H TBC1D22A 25348397 N/A physical interaction ComPPI
SUPT6H ATL3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
SUPT6H MCPH1 25348397 N/A physical interaction ComPPI
RNF20 SUPT6H 25348397 N/A physical interaction ComPPI
HSPA5 SUPT6H 24234451 30021884 physical association cross-linking study IntAct
H2AC12 SUPT6H 24234451 30021884 physical association cross-linking study IntAct

Source Target Pmid Interactiontype Methods Database
URS00009B6B52 SUPT6H 27087310 direct interaction,inhibition N/A NPInter

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