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GENE：THAP4

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol THAP4
FullNmae THAP domain containing 4
LocusType gene with protein product
Status Approved
HGNC_id HGNC:23187
EnsembleID ENSG00000176946
Uniprot Q8WY91

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
THAP4 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
THAP4 GO:0003677,GO:0005515,GO:0005575,GO:0005654,GO:0005829,GO:0006570,GO:0020037,GO:0042126,GO:0042802,GO:0046872,GO:0062213,GO:0070026

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
AR THAP4 20610535 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 THAP4 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
HIF1A THAP4 19828020 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
MYC THAP4 18414489 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
CEBPA THAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF THAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 THAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS THAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A THAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF THAP4 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000486E0B THAP4 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
HSPA8 THAP4 25348397 N/A physical interaction ComPPI
LAT THAP4 25348397 N/A two hybrid ComPPI
ACTB THAP4 25348397 N/A physical interaction ComPPI
HSP90AB1 THAP4 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
CD81 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PPP1R15A THAP4 24234451 25348397 29109149 association anti tag coimmunoprecipitation ComPPI,IntAct
CPNE2 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
HSP90AA1 THAP4 25348397 N/A physical interaction ComPPI
HNRNPL THAP4 25348397 N/A physical interaction ComPPI
MAPK6 THAP4 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SYP THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
PLP2 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
CORO2A THAP4 25348397 N/A physical interaction ComPPI
MS4A1 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRIM25 THAP4 25348397 N/A physical interaction ComPPI
TNFRSF10D THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
IGFBP5 THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
AIFM1 THAP4 25348397 N/A physical interaction ComPPI
THAP4 APP 25348397 N/A physical interaction ComPPI
THAP4 LPAR3 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TTPA THAP4 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
TRADD THAP4 24234451 30561431 association virotrap IntAct
H1-1 THAP4 24234451 30021884 physical association cross-linking study IntAct

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