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GENE：TMCO6

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TMCO6
FullNmae transmembrane and coiled-coil domains 6
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28814
EnsembleID ENSG00000113119
Uniprot Q96DC7

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TMCO6 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
TMCO6 autosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TMCO6 GO:0005515,GO:0006606,GO:0016020,GO:0061608

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 TMCO6 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA2 TMCO6 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA TMCO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TMCO6 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00003CF1AD TMCO6 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
UBB TMCO6 25348397 N/A physical interaction ComPPI
LSM5 TMCO6 25348397 N/A physical interaction ComPPI
UBQLN1 TMCO6 14525934 16189514 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct

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