Gene Information gene info

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GENE：TWF2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol TWF2
FullNmae twinfilin actin binding protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:9621
EnsembleID ENSG00000247596
Uniprot Q6IBS0

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
TWF2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
TWF2 GO:0003723,GO:0003785,GO:0003785,GO:0005080,GO:0005515,GO:0005524,GO:0005546,GO:0005737,GO:0005737,GO:0005737,GO:0005884,GO:0010591,GO:0010592,GO:0010976,GO:0010976,GO:0030016,GO:0030016,GO:0030027,GO:0030030,GO:0030042,GO:0030175,GO:0030426,GO:0030837,GO:0032420,GO:0032532,GO:0032956,GO:0042989,GO:0042989,GO:0045296,GO:0045773,GO:0048471,GO:0051015,GO:0051016,GO:0051016,GO:0070062,GO:0071300,GO:0071363

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
FOXJ1 TWF2 21988832 23180781 physical association two hybrid InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 TWF2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 TWF2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 TWF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF TWF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 TWF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 TWF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS TWF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A TWF2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA TWF2 N/A trascriptional regulation,stimulation inferred by curator TFlink
CREB1 TWF2 N/A trascriptional regulation,stimulation inferred by curator TFlink
ELK1 TWF2 N/A trascriptional regulation,stimulation inferred by curator TFlink
ETS2 TWF2 N/A trascriptional regulation,stimulation inferred by curator TFlink
JUN TWF2 N/A trascriptional regulation,stimulation inferred by curator TFlink
RELA TWF2 N/A trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00001D69F6 TWF2 20571053 rna interference,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay miRSponge
URS00001D69F6 TWF2 20571053 25416803 mrna cleavage,inhibition array technology,western blot,northern blot,quantitative reverse transcription pcr,miRNA interference luciferase reporter assay TarBase
URS00005651EE TWF2 23622248 25416803 mrna cleavage,inhibition clash TarBase

Source Target Pmid Interactiontype Methods Database
PLAA TWF2 25348397 N/A physical interaction ComPPI
BAG3 TWF2 25348397 N/A physical interaction ComPPI
ACTB TWF2 25348397 N/A physical interaction ComPPI
KRT31 TWF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBL7 TWF2 25348397 N/A physical interaction ComPPI
TBCB TWF2 25348397 N/A physical interaction ComPPI
ARHGDIA TWF2 21900206 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
CDH1 TWF2 25348397 N/A physical interaction ComPPI
ILK TWF2 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
PDIA4 TWF2 25348397 N/A physical interaction ComPPI
CAPZA1 TWF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UHRF2 TWF2 25348397 N/A physical interaction ComPPI
PKM TWF2 25348397 N/A physical interaction ComPPI
ERC1 TWF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
UBA6 TWF2 25348397 N/A physical interaction ComPPI
UBAC1 TWF2 25348397 N/A physical interaction ComPPI
XPO1 TWF2 25348397 N/A physical interaction ComPPI
YWHAE TWF2 25348397 N/A physical interaction ComPPI
CAPN2 TWF2 25348397 N/A physical interaction ComPPI
POT1 TWF2 21044950 24234451 25348397 physical association physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
CAP1 TWF2 25348397 N/A physical interaction ComPPI
TERF2IP TWF2 21044950 24234451 25348397 physical association pull down,physical interaction,bimolecular fluorescence complementation ComPPI,IntAct
SYNPO TWF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
IQCB1 TWF2 21565611 24234451 25348397 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
PAN2 TWF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
TLN2 TWF2 25348397 N/A physical interaction ComPPI
STYX TWF2 25348397 N/A physical interaction ComPPI
CAP2 TWF2 25348397 N/A physical interaction ComPPI
MYH9 TWF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
MYO1C TWF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
ACTA2 TWF2 25348397 N/A physical interaction ComPPI
ARIH2 TWF2 25348397 N/A physical interaction ComPPI
ERCC1 TWF2 25348397 N/A physical interaction ComPPI
HK1 TWF2 25348397 N/A physical interaction ComPPI
UTP6 TWF2 25348397 N/A physical interaction ComPPI
PSMD9 TWF2 25348397 N/A physical interaction ComPPI
CHGB TWF2 14525934 16169070 24234451 25348397 physical association two hybrid,physical interaction,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid ComPPI,HPRD,IntAct
LYAR TWF2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
VPS36 TWF2 25348397 N/A physical interaction ComPPI
BCL7A TWF2 25348397 N/A physical interaction ComPPI
LIMA1 TWF2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
UBXN1 TWF2 25348397 N/A physical interaction ComPPI
ASNS TWF2 25348397 N/A physical interaction ComPPI
MCTS1 TWF2 25348397 N/A physical interaction ComPPI
TWF2 VRK3 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 KRT85 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 ELOVL1 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 KRT82 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 CAPZB 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 CAPZA2 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 ACTR3B 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 KRT36 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation,physical interaction ComPPI,IntAct
TWF2 FOXJ1 21988832 24234451 25348397 physical association two hybrid,physical interaction,two hybrid array ComPPI,IntAct
TWF2 PLPBP 25348397 N/A physical interaction ComPPI
TWF2 SCPEP1 25348397 N/A physical interaction ComPPI
TWF2 TUBB2A 25348397 N/A physical interaction ComPPI
TWF2 APEX1 25348397 N/A physical interaction ComPPI
TWF2 OGFOD1 25348397 N/A physical interaction ComPPI
TWF2 NANOGP8 25348397 N/A physical interaction ComPPI
TWF2 NANOG 25348397 N/A physical interaction ComPPI
TWF2 ACTBL2 25348397 N/A physical interaction ComPPI
TWF2 BCL7C 25348397 N/A physical interaction ComPPI
TWF2 TMOD3 25348397 N/A physical interaction ComPPI
TWF2 ACTC1 25348397 N/A physical interaction ComPPI
TWF2 PLEKHA7 24234451 25348397 28877994 association anti bait coimmunoprecipitation ComPPI,IntAct
STK26 TWF2 25348397 N/A physical interaction ComPPI
HMGN2 TWF2 24234451 30021884 physical association cross-linking study IntAct

Visualization










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