Gene Information gene info

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GENE：ZNF74

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ZNF74
FullNmae zinc finger protein 74
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13144
EnsembleID ENSG00000185252
Uniprot Q16587

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ZNF74 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
ZNF74 GO:0000978,GO:0000981,GO:0003723,GO:0005634,GO:0005654,GO:0006355,GO:0006357,GO:0015629,GO:0046872

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ZNF74 hsa:7625 path:hsa05168 Herpes simplex virus 1 infection - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ZNF74 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 ZNF74 17531812 18971253 trascriptional regulation,stimulation chromatin immunoprecipitation array,inferred by curator TFlink
ETS1 ZNF74 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
PRDM14 ZNF74 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
EGR1 ZNF74 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS ZNF74 18971253 trascriptional regulation,stimulation inferred by curator TFlink
ZNF263 ZNF74 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000122ED0 ZNF74 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS000054A671 ZNF74 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS00000FB5B8 ZNF74 22100165 25416803 mrna cleavage,inhibition clip TarBase
URS000075ABF4 ZNF74 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS00001F0C23 ZNF74 20371350 23446348 23592263 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000008A99 ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000221168 ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00003380CC ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00005CC20C ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048D44E ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000075C4B1 ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000F31F4 ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000CC005 ZNF74 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TRIM28 ZNF74 25361965 interaction type N/A PTMCode2
ZNF74 TRIM28 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
HSP90AB1 ZNF74 22939624 24234451 25348397 physical association luminescence based mammalian interactome mapping ComPPI,IntAct
HSP90AA1 ZNF74 25348397 N/A physical interaction ComPPI
TRIM28 ZNF74 12684500 14525934 25348397 N/A experimental interaction detection,physical interaction,in vivo ComPPI,HPRD
POLR2A ZNF74 11313019 14525934 25348397 27898060 9346935 N/A experimental interaction detection,physical interaction,in vitro,in vivo ComPPI,HPRD,OmniPath
ZNF74 HSP90AA2P 25348397 N/A physical interaction ComPPI
ZNF74 VWCE 25348397 N/A physical interaction ComPPI

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