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GENE：ATP5MC3

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol ATP5MC3
FullNmae ATP synthase membrane subunit c locus 3
LocusType gene with protein product
Status Approved
HGNC_id HGNC:843
EnsembleID ENSG00000154518
Uniprot P48201

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
ATP5MC3 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
ATP5MC3 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
ATP5MC3 GO:0000276,GO:0005515,GO:0005741,GO:0005743,GO:0005753,GO:0008289,GO:0015078,GO:0015986,GO:0015986,GO:1902600

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
ATP5MC3 hsa:518 path:hsa00190 Oxidative phosphorylation - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa01100 Metabolic pathways - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa04714 Thermogenesis - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05010 Alzheimer disease - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05012 Parkinson disease - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05014 Amyotrophic lateral sclerosis - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05016 Huntington disease - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05020 Prion disease - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05022 Pathways of neurodegeneration - multiple diseases - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05208 Chemical carcinogenesis - reactive oxygen species - Homo sapiens (human)
ATP5MC3 hsa:518 path:hsa05415 Diabetic cardiomyopathy - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
ETS1 ATP5MC3 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
GATA1 ATP5MC3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
GATA2 ATP5MC3 19941826 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXA1 ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOXP1 ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A ATP5MC3 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS0000070B1D ATP5MC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00000EC1BE ATP5MC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS00001A7F58 ATP5MC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000239117 ATP5MC3 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000171CD1 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000041CB9C ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000040EE1D ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F0F49 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000007D64A ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000F6E49 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000012A1DD ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000171525 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000055BBE5 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000045B99E ATP5MC3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000AB32B ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000010F787 ATP5MC3 20371350 21572407 22012620 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00004977C5 ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000075A513 ATP5MC3 20371350 21572407 22012620 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000048BA36 ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000521626 ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS000018C928 ATP5MC3 20371350 21572407 22012620 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00000CBE63 ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS0000081E1F ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00003BBF48 ATP5MC3 20371350 21572407 22012620 22927820 23313552 23446348 23592263 24398324 25416803 26701625 27292025 mrna cleavage,inhibition clip TarBase
URS00001EFEC1 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000061E50F ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000475586 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002ECEE4 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E1509 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00001E0AEA ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002E628F ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000101787 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000260A3A ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000038718E ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00003A8BB2 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000080D0A ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000008AA34 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00002C02E4 ATP5MC3 21572407 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000039A25B ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075B13F ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000075AEA5 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00004283FE ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000118224 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS000037B2E0 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00000319E1 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS0000496C56 ATP5MC3 21572407 25416803 mrna cleavage,inhibition clip TarBase
URS00005CCD18 ATP5MC3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00003FA24D ATP5MC3 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS0000568FF8 ATP5MC3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000040780F ATP5MC3 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000330617 ATP5MC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00001B341F ATP5MC3 22473208 25416803 mrna cleavage,inhibition clip TarBase
URS00005ACA7C ATP5MC3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS00000C5969 ATP5MC3 25416803 27292025 mrna cleavage,inhibition clip TarBase
URS000047A67D ATP5MC3 25416803 27292025 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
ATP5F1B ATP5MC3 25348397 N/A physical interaction ComPPI
GOLGA4 ATP5MC3 25348397 N/A physical interaction ComPPI
MTNR1A ATP5MC3 25348397 N/A physical interaction ComPPI
ATP5MC3 MOV10 25348397 N/A physical interaction ComPPI
ATP5MC3 NXF1 25348397 N/A physical interaction ComPPI
ATP5MC3 ATP5F1D 25348397 N/A physical interaction ComPPI

Visualization










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