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GENE：EMC2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol EMC2
FullNmae ER membrane protein complex subunit 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:28963
EnsembleID ENSG00000104412
Uniprot Q15006

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
EMC2 immunogenic 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EMC2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature
EMC2 ferroptosis 36341760 The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns. regulator signature

Go Annotation:

GeneSymbol Go id
EMC2 GO:0005515,GO:0005737,GO:0005783,GO:0005789,GO:0005789,GO:0032977,GO:0042406,GO:0045050,GO:0045050,GO:0071816,GO:0072546,GO:0072546,GO:0072546,GO:0072546

Protein-Protein Interaction(String):

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
EMC2 EGR1 19032775 23180781 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
ETS1 EMC2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 EMC2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
SMARCA4 EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F4 EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
MITF EMC2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS000021D7C8 EMC2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS000075B538 EMC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS000048BA36 EMC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000160683 EMC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000254A6 EMC2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00001FC26E EMC2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
SF3A3 EMC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
RBM17 EMC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
HNRNPC EMC2 25348397 N/A two hybrid ComPPI
EMC2 EMC9 14525934 16189514 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,validated two hybrid,two hybrid ComPPI,HPRD,IntAct
EMC2 EMC8 14525934 16189514 24234451 25348397 26496610 30021884 association,physical association anti tag coimmunoprecipitation,cross-linking study,physical interaction,two hybrid array,two hybrid pooling approach,two hybrid fragment pooling approach,two hybrid prey pooling approach,two hybrid ComPPI,HPRD,IntAct
EMC2 CFTR 25348397 N/A physical interaction ComPPI
EMC2 FBXO6 25348397 N/A physical interaction ComPPI
EMC2 IKZF3 24234451 25348397 25416956 physical association physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
EMC2 CCDC33 25348397 N/A physical interaction ComPPI
EMC2 CCDC8 25348397 N/A physical interaction ComPPI
EMC2 EMC7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 DERL2 25348397 N/A physical interaction ComPPI
EMC2 EMC1 25348397 N/A physical interaction ComPPI
EMC2 EMC3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MMGT1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 EMC10 25348397 N/A physical interaction ComPPI
EMC2 EMC6 25348397 N/A physical interaction ComPPI
EMC2 UBAC2 25348397 N/A physical interaction ComPPI
EMC2 EMC4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 CIB2 25348397 N/A physical interaction ComPPI
EMC2 SLC18A1 25348397 N/A physical interaction ComPPI
EMC2 NTRK1 25348397 N/A physical interaction ComPPI
EMC2 TCTN2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 TCTN3 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 EVC2 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 TMEM237 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 TMEM17 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 TMEM216 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 TMEM67 24234451 25348397 26638075 association physical interaction,proximity-dependent biotin identification ComPPI,IntAct
EMC2 ABCF1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 ADARB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 ATP5PB 25348397 N/A physical interaction ComPPI
EMC2 AP3S1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 FANCD2 25348397 N/A anti tag coimmunoprecipitation,physical interaction ComPPI
EMC2 FUS 25348397 N/A physical interaction ComPPI
EMC2 HELLS 25348397 N/A physical interaction ComPPI
EMC2 HMGA1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 HNRNPA2B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 HNRNPAB 25348397 N/A physical interaction ComPPI
EMC2 IMPDH1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 IMPDH2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 KTN1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 LIG3 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 PHB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 POLB 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MED1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 RFC1 25348397 N/A physical interaction ComPPI
EMC2 HLTF 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SPG7 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 TNFAIP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 XPC 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SF1 25348397 N/A physical interaction ComPPI
EMC2 SF3A2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 ZRSR2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 RBM10 25348397 N/A physical interaction ComPPI
EMC2 AGPS 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 VAPA 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MED14 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MED17 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SAFB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MED24 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MED16 25348397 N/A physical interaction ComPPI
EMC2 TSSC4 25348397 N/A physical interaction ComPPI
EMC2 RBM6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 RBM5 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SF3A1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 CD2BP2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 EMG1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 CHERP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 CKAP4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SF3B2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 PHB2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 DNAJC8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SCAF8 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SF3B1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 TBL2 25348397 N/A physical interaction ComPPI
EMC2 SIRT6 25348397 N/A physical interaction ComPPI
EMC2 PCF11 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MAP3K20 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 LRRC59 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 RABL6 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 CCAR1 25348397 N/A physical interaction ComPPI
EMC2 DDX28 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 PCNP 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 ZMAT3 25348397 N/A physical interaction ComPPI
EMC2 MRPS9 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 TRIR 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 WDR77 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 MRM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 RIOK1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 SPRTN 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 NSRP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 ASCC2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 PYM1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 HDGFL2 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 PHF5A 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 PPIL4 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 CCDC124 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 NOPCHAP1 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 BAP18 25348397 N/A physical interaction ComPPI
EMC2 C19ORF47 25348397 N/A physical interaction ComPPI
EMC2 B3GLCT 24234451 25348397 26496610 association anti tag coimmunoprecipitation,physical interaction ComPPI,IntAct
EMC2 RHOU 25348397 N/A physical interaction ComPPI
EMC2 COQ9 25348397 N/A physical interaction ComPPI
EMC2 TRDN 25348397 N/A physical interaction ComPPI
EMC2 SDHA 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
EMC2 EDEM3 25348397 N/A physical interaction ComPPI
EMC2 TNFRSF1B 14743216 24234451 25348397 physical association tandem affinity purification ComPPI,IntAct
EMC2 PCDHB12 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EMC2 SH3BP5L 24234451 25348397 physical association two hybrid,two hybrid array,two hybrid prey pooling approach ComPPI,IntAct
EMC2 HSCB 24234451 25348397 28380382 association anti bait coimmunoprecipitation ComPPI,IntAct
EMC2 CANX 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EMC2 LAMP1 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EMC2 LMNA 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
EMC2 COX6B1 24234451 25348397 27499296 association anti tag coimmunoprecipitation ComPPI,IntAct

Visualization










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