GeneInfo:
GeneAttribute
GeneDescription
GeneSymbol
ACSF2
FullNmae
acyl-CoA synthetase family member 2
LocusType
gene with protein product
Status
Approved
HGNC_id
HGNC:26101
EnsembleID
ENSG00000167107
Uniprot
Q96CM8
Protein Structure:
Gene Description in Publicaton:
GeneSymbol
CellDeathType
PMID
Description
GeneType
ACSF2
ferroptosis
38538696
The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore)
retulator signature
ACSF2
ferroptosis
36341760
The PCD-related genes contained the key regulatory genes of twelve PCD patterns which is mentioned above. Genes were collected from GSEA gene sets, KEGG, review articles, and manual collation [10]. The ultimate gene list was the concatenation regulatory genes of twelve PCD patterns.
regulator signature
Go Annotation:
GeneSymbol
Go id
ACSF2
GO:0001676,GO:0004467,GO:0005515,GO:0005524,GO:0005759,GO:0006631,GO:0006637,GO:0031956,GO:0031956,GO:0047760
Protein-Protein Interaction(String):
Signalink 3.0 modificators
Source
Target
Pmid
Interactiontype
Methods
Database
ETS1
ACSF2
18971253
20019798
trascriptional regulation,stimulation
inferred by curator,chromatin immunoprecipitation assay
TFlink
SMARCA4
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CEBPA
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
CTCF
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
EGR1
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOXA1
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
FOS
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
HNF4A
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
MITF
ACSF2
18971253
trascriptional regulation,stimulation
inferred by curator
TFlink
Source
Target
Pmid
Interactiontype
Methods
Database
URS0000237AF9
ACSF2
18185580
25416803
mrna cleavage,inhibition
array technology
TarBase
URS000003ABC4
ACSF2
19088304
25416803
mrna cleavage,inhibition
array technology
TarBase
URS00000753AD
ACSF2
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS000011A030
ACSF2
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000435A77
ACSF2
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS0000458AD2
ACSF2
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
URS000054A671
ACSF2
23592263
25416803
mrna cleavage,inhibition
clip
TarBase
Source
Target
Pmid
Interactiontype
Methods
Database
AGTRAP
ACSF2
24234451
25348397
25416956
physical association
physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid
ComPPI,IntAct
CREB3
ACSF2
21516116
24234451
25348397
physical association
two hybrid,physical interaction
ComPPI,IntAct
GNB2
ACSF2
25348397
N/A
physical interaction
ComPPI
SENP2
ACSF2
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
HSPD1
ACSF2
25348397
N/A
physical interaction
ComPPI
SLC25A10
ACSF2
25348397
N/A
physical interaction
ComPPI
MRPL12
ACSF2
25348397
N/A
physical interaction
ComPPI
SIRT4
ACSF2
24234451
25348397
25525879
association
anti tag coimmunoprecipitation
ComPPI,IntAct
RDH10
ACSF2
24234451
25348397
physical association
two hybrid,two hybrid array,two hybrid prey pooling approach
ComPPI,IntAct
CMTM5
ACSF2
21516116
24234451
25348397
25416956
physical association
two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid
ComPPI,IntAct
H1-5
ACSF2
24234451
30021884
physical association
cross-linking study
IntAct
Visualization