Gene Information gene info

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GENE：DUOX2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol DUOX2
FullNmae dual oxidase 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:13273
EnsembleID ENSG00000140279
Uniprot Q9NRD8

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
DUOX2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
DUOX2 GO:0004601,GO:0005509,GO:0005515,GO:0005783,GO:0005829,GO:0005886,GO:0005886,GO:0005886,GO:0005886,GO:0006590,GO:0006590,GO:0006952,GO:0006979,GO:0009615,GO:0009986,GO:0016174,GO:0016174,GO:0016174,GO:0016175,GO:0016324,GO:0019221,GO:0019221,GO:0020037,GO:0031252,GO:0042335,GO:0042446,GO:0042554,GO:0042554,GO:0042744,GO:0043020,GO:0045177,GO:0050665,GO:0051591,GO:0051591,GO:0070062,GO:0070161,GO:0090303,GO:0098869,GO:0106293,GO:0106294,GO:2000147

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
DUOX2 hsa:50506 path:hsa04918 Thyroid hormone synthesis - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
DUOX2 NOD2 19759286 23180781 physical association anti tag coimmunoprecipitation InnateDB
DUOX2 RELA 23180781 23296709 physical association anti tag coimmunoprecipitation InnateDB

Source Target Pmid Interactiontype Methods Database
E2F4 DUOX2 11799066 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
CEBPA DUOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF DUOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 DUOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS DUOX2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00002CEB74 DUOX2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS00000011DF DUOX2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000224AEA DUOX2 23824327 25416803 mrna cleavage,inhibition clip TarBase
URS0000284586 DUOX2 23824327 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
TXNDC11 DUOX2 14525934 15561711 24234451 25348397 colocalization anti bait coimmunoprecipitation,experimental interaction detection,in vivo ComPPI,HPRD,IntAct
DUOX2 NOD2 19759286 27898060 N/A N/A OmniPath

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