Gene Information gene info

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GENE：SCP2

GeneInfo:

GeneAttribute GeneDescription
GeneSymbol SCP2
FullNmae sterol carrier protein 2
LocusType gene with protein product
Status Approved
HGNC_id HGNC:10606
EnsembleID ENSG00000116171
Uniprot P22307

Protein Structure:

Gene Description in Publicaton:

GeneSymbol CellDeathType PMID Description GeneType
SCP2 ferroptosis 38538696 The 18 RCD signatures collected from previous studies. Supplementary Table of Figures.xlsx (https://github.com/zwxiangya/RCDscore) retulator signature

Go Annotation:

GeneSymbol Go id
SCP2 GO:0000062,GO:0003988,GO:0005102,GO:0005515,GO:0005654,GO:0005739,GO:0005777,GO:0005777,GO:0005782,GO:0005783,GO:0005829,GO:0006635,GO:0006699,GO:0008206,GO:0015485,GO:0015914,GO:0016020,GO:0032367,GO:0032385,GO:0032991,GO:0033540,GO:0033814,GO:0036042,GO:0036109,GO:0050632,GO:0050632,GO:0050632,GO:0050633,GO:0070538,GO:1901373

KEGG Annotation:

GeneSymbol GeneID Pathway Pathway Name
SCP2 hsa:6342 path:hsa00120 Primary bile acid biosynthesis - Homo sapiens (human)
SCP2 hsa:6342 path:hsa01040 Biosynthesis of unsaturated fatty acids - Homo sapiens (human)
SCP2 hsa:6342 path:hsa01100 Metabolic pathways - Homo sapiens (human)
SCP2 hsa:6342 path:hsa01212 Fatty acid metabolism - Homo sapiens (human)
SCP2 hsa:6342 path:hsa03320 PPAR signaling pathway - Homo sapiens (human)
SCP2 hsa:6342 path:hsa04146 Peroxisome - Homo sapiens (human)

Protein-Protein Interaction(String):

Gene-Drug Network:

Signalink 3.0 modificators

Source Target Pmid Interactiontype Methods Database
E2F4 SCP2 17531812 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
ETS1 SCP2 18971253 20019798 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
YBX1 SCP2 19151767 trascriptional regulation,stimulation chromatin immunoprecipitation assay TFlink
FOXP3 SCP2 20554955 trascriptional regulation,stimulation chromatin immunoprecipitation array TFlink
PRDM14 SCP2 18971253 20953172 trascriptional regulation,stimulation inferred by curator,chromatin immunoprecipitation assay TFlink
SMARCA4 SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CEBPA SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
CTCF SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
E2F1 SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
EGR1 SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
FOS SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
GATA2 SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
HNF4A SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink
RUNX1 SCP2 18971253 trascriptional regulation,stimulation inferred by curator TFlink

Source Target Pmid Interactiontype Methods Database
URS00004E008F SCP2 20371350 25416803 mrna cleavage,inhibition nucleotide sequence identification TarBase
URS000003ABC4 SCP2 19088304 25416803 mrna cleavage,inhibition array technology TarBase
URS0000239117 SCP2 23622248 25416803 mrna cleavage,inhibition clash TarBase
URS0000065D58 SCP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00000B59A2 SCP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000005CF5F SCP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS00001DE669 SCP2 20371350 25416803 mrna cleavage,inhibition clip TarBase
URS000028DE3F SCP2 20371350 25416803 mrna cleavage,inhibition clip TarBase

Source Target Pmid Interactiontype Methods Database
CAV1 SCP2 25361965 interaction type N/A PTMCode2
SCP2 CAV1 25361965 interaction type N/A PTMCode2

Source Target Pmid Interactiontype Methods Database
UBL4A SCP2 25348397 N/A physical interaction ComPPI
UXT SCP2 25348397 N/A physical interaction ComPPI
RAB8A SCP2 25348397 N/A physical interaction ComPPI
ACOX1 SCP2 10856712 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
PITPNA SCP2 25348397 N/A physical interaction ComPPI
CAV1 SCP2 14525934 15182174 24234451 25348397 27898060 colocalization,physical association two hybrid,experimental interaction detection,fluorescent resonance energy transfer,physical interaction,in vitro ComPPI,HPRD,IntAct,OmniPath
RRBP1 SCP2 25348397 N/A physical interaction ComPPI
HNRNPL SCP2 25348397 N/A physical interaction ComPPI
PDHA1 SCP2 24234451 25348397 29128334 association cross-linking study,physical interaction ComPPI,IntAct
VDAC2 SCP2 25348397 N/A physical interaction ComPPI
SCP2 EHHADH 10856712 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SCP2 ACAA2 10856712 14525934 25348397 N/A experimental interaction detection,in vitro ComPPI,HPRD
SCP2 CACNA1A 21078624 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SCP2 ELAVL1 25348397 N/A physical interaction ComPPI
SCP2 HSD17B4 24234451 25348397 30021884 physical association cross-linking study,physical interaction ComPPI,IntAct
SCP2 MRPS28 25348397 N/A physical interaction ComPPI
SCP2 ACAA1 25348397 N/A physical interaction ComPPI
SCP2 STX7 25348397 N/A physical interaction ComPPI
SCP2 RBMS1 25348397 N/A physical interaction ComPPI
SCP2 VDAC3 25348397 N/A physical interaction ComPPI
SCP2 TBL2 25348397 N/A physical interaction ComPPI
SCP2 SCO2 25348397 N/A physical interaction ComPPI
SCP2 SUGP1 25348397 N/A physical interaction ComPPI
SCP2 ECI2 25348397 N/A physical interaction ComPPI
SCP2 RAB31 25348397 N/A physical interaction ComPPI
SCP2 NDUFA7 25348397 N/A physical interaction ComPPI
SCP2 IDH3G 25348397 N/A physical interaction ComPPI
SCP2 SRRM2 25348397 N/A physical interaction ComPPI
SCP2 MRRF 25348397 N/A physical interaction ComPPI
SCP2 MPLKIP 25348397 N/A physical interaction ComPPI
SCP2 PEX5 25348397 N/A physical interaction ComPPI
SCP2 TRIP13 21516116 24234451 25348397 25416956 physical association two hybrid,physical interaction,two hybrid array,two hybrid prey pooling approach,validated two hybrid ComPPI,IntAct
SCP2 MYO5A 25348397 N/A physical interaction ComPPI
SCP2 MYO5C 25348397 N/A physical interaction ComPPI
SCP2 URI1 25348397 N/A physical interaction ComPPI
SCP2 PDRG1 25348397 N/A physical interaction ComPPI
SCP2 HMGCS1 25348397 N/A physical interaction ComPPI
SCP2 MED20 25348397 N/A physical interaction ComPPI
SCP2 CREB3 21516116 24234451 25348397 physical association two hybrid,physical interaction ComPPI,IntAct
SCP2 EPB41 17353931 24234451 25348397 physical association anti bait coimmunoprecipitation ComPPI,IntAct
SCP2 PEX14 20531392 24234451 25348397 colocalization fluorescence microscopy ComPPI,IntAct
SCP2 TYSND1 25348397 N/A anti tag coimmunoprecipitation ComPPI
SCP2 SF1 24234451 25348397 26420826 physical association two hybrid fragment pooling approach ComPPI,IntAct
SCP2 CAT 24234451 25348397 29568061 association proximity-dependent biotin identification ComPPI,IntAct
TIMM44 SCP2 25348397 N/A physical interaction ComPPI
SEPTIN9 SCP2 25348397 N/A physical interaction ComPPI
POLR1A SCP2 25348397 N/A physical interaction ComPPI
AGPS SCP2 25348397 N/A physical interaction ComPPI
SCP2 URB2 24234451 30021884 physical association cross-linking study IntAct
FOXO3 SCP2 17522590 27898060 stimulant N/A OmniPath

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